eF-site ID 5fe8-B PDB Code 5fe8 Chain B click to enlarge Title Crystal structure of human PCAF bromodomain in complex with compound SL1126 (compound 12) Classification SIGNALING PROTEIN Compound Histone acetyltransferase KAT2B Source Homo sapiens (Human) (KAT2B_HUMAN) Sequence B:  DPDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEV IRFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYN PPESEYYKCANILEKFFFSKIKEAGLID Description Functional site 1) chain B residue 771 type sequence K description binding site for residue EDO B 901 source : AC6 2) chain B residue 774 type sequence S description binding site for residue EDO B 901 source : AC6 3) chain B residue 776 type sequence R description binding site for residue EDO B 902 source : AC7 4) chain B residue 727 type sequence Q description binding site for residue EDO B 903 source : AC8 5) chain B residue 728 type sequence L description binding site for residue EDO B 903 source : AC8 6) chain B residue 731 type sequence T description binding site for residue EDO B 903 source : AC8 7) chain B residue 776 type sequence R description binding site for residue EDO B 904 source : AC9 8) chain B residue 779 type sequence N description binding site for residue EDO B 904 source : AC9 9) chain B residue 747 type sequence P description binding site for residue DMS B 905 source : AD1 10) chain B residue 803 type sequence N description binding site for residue DMS B 905 source : AD1

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