eF-site ID 5fe2-AB PDB Code 5fe2 Chain A, B click to enlarge Title Crystal structure of human PCAF bromodomain in complex with fragment BR013 (fragment 3) Classification SIGNALING PROTEIN Compound Histone acetyltransferase KAT2B Source Homo sapiens (Human) (KAT2B_HUMAN) Sequence A:  PDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNP PESEYYKCANILEKFFFSKIKEAGLID B:  PDQLYSTLKSILQQVKSHQSAWPFMEPVKRTEAPGYYEVI RFPMDLKTMSERLKNRYYVSKKLFMADLQRVFTNCKEYNP PESEYYKCANILEKFFFSKIKEAGLID Description Functional site 1) chain A residue 747 type sequence P description binding site for residue 5WV A 901 source : AC1 2) chain A residue 748 type sequence F description binding site for residue 5WV A 901 source : AC1 3) chain A residue 756 type sequence E description binding site for residue 5WV A 901 source : AC1 4) chain A residue 803 type sequence N description binding site for residue 5WV A 901 source : AC1 5) chain A residue 733 type sequence K description binding site for residue EDO A 902 source : AC2 6) chain A residue 737 type sequence Q description binding site for residue EDO A 902 source : AC2 7) chain A residue 740 type sequence K description binding site for residue EDO A 902 source : AC2 8) chain A residue 774 type sequence S description binding site for residue EDO A 902 source : AC2 9) chain A residue 777 type sequence L description binding site for residue EDO A 902 source : AC2 10) chain B residue 747 type sequence P description binding site for residue 5WV B 901 source : AC3 11) chain B residue 756 type sequence E description binding site for residue 5WV B 901 source : AC3 12) chain B residue 757 type sequence A description binding site for residue 5WV B 901 source : AC3 13) chain B residue 803 type sequence N description binding site for residue 5WV B 901 source : AC3 14) chain B residue 809 type sequence Y description binding site for residue 5WV B 901 source : AC3 15) chain B residue 743 type sequence Q description binding site for residue EDO B 902 source : AC4 16) chain B residue 744 type sequence S description binding site for residue EDO B 902 source : AC4 17) chain B residue 815 type sequence I description binding site for residue EDO B 902 source : AC4 18) chain B residue 754 type sequence R description binding site for residue EDO B 903 source : AC5 19) chain A residue 808 type sequence E description binding site for residue EDO B 904 source : AC6 20) chain B residue 727 type sequence Q description binding site for residue EDO B 904 source : AC6 21) chain A residue 745-802 type prosite sequence AWPFMEPVKRTEAPGYYEVIRFPMDLKTMSERLKNRYYVS KKLFMADLQRVFTNCKEY description BROMODOMAIN_1 Bromodomain signature. AwpFmepvKrteap..GYYevIrfpMdlktMserlknry..Yvskklfmadlqr.VftNCkeY source prosite : PS00633

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