eF-site ID 5fcr-ABCD PDB Code 5fcr Chain A, B, C, D click to enlarge Title MOUSE COMPLEMENT FACTOR D Classification HYDROLASE Compound Complement factor D Source Mus musculus (Mouse) (CFAD_MOUSE) Sequence A:  ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAA HCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHP GSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY HDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTW GSRVCGNGKKPGVYTRVSSYRMWIENITNG B:  ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAA HCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHP GSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY HDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTW GSRVCGNGKKPGVYTRVSSYRMWIENITNG C:  ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAA HCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHP GSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY HDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTW GSRVCGNGKKPGVYTRVSSYRMWIENITN D:  ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAA HCMDGVTDDDSVQVLLGAHSLSAPEPYKRWYDVQSVVPHP GSRPDSLEDDLILFKLSQNASLGPHVRPLPLQYEDKEVEP GTLCDVAGWGVVTHAGRRPDVLHQLRVSIMNRTTCNLRTY HDGVVTINMMCAESNRRDTCRGDSGSPLVCGDAVEGVVTW GSRVCGNGKKPGVYTRVSSYRMWIENITNG Description Functional site 1) chain B residue 91 type sequence H description binding site for residue EPE B 301 source : AC1 2) chain B residue 100 type sequence E description binding site for residue EPE B 301 source : AC1 3) chain B residue 101 type sequence D description binding site for residue EPE B 301 source : AC1 4) chain B residue 179 type sequence N description binding site for residue EPE B 301 source : AC1 5) chain B residue 233 type sequence S description binding site for residue EPE B 301 source : AC1 6) chain B residue 234 type sequence Y description binding site for residue EPE B 301 source : AC1 7) chain B residue 236 type sequence M description binding site for residue EPE B 301 source : AC1 8) chain B residue 237 type sequence W description binding site for residue EPE B 301 source : AC1 9) chain B residue 21 type sequence E description binding site for residue GOL B 302 source : AC2 10) chain B residue 150 type sequence R description binding site for residue GOL B 302 source : AC2 11) chain B residue 152 type sequence P description binding site for residue GOL B 302 source : AC2 12) chain B residue 153 type sequence D description binding site for residue GOL B 302 source : AC2 13) chain B residue 154 type sequence V description binding site for residue GOL B 302 source : AC2 14) chain B residue 156 type sequence H description binding site for residue GOL B 302 source : AC2 15) chain C residue 91 type sequence H description binding site for residue EPE C 301 source : AC3 16) chain C residue 100 type sequence E description binding site for residue EPE C 301 source : AC3 17) chain C residue 101 type sequence D description binding site for residue EPE C 301 source : AC3 18) chain C residue 179 type sequence N description binding site for residue EPE C 301 source : AC3 19) chain C residue 233 type sequence S description binding site for residue EPE C 301 source : AC3 20) chain C residue 234 type sequence Y description binding site for residue EPE C 301 source : AC3 21) chain C residue 236 type sequence M description binding site for residue EPE C 301 source : AC3 22) chain C residue 237 type sequence W description binding site for residue EPE C 301 source : AC3 23) chain C residue 150 type sequence R description binding site for residue SO4 C 302 source : AC4 24) chain C residue 152 type sequence P description binding site for residue SO4 C 302 source : AC4 25) chain C residue 153 type sequence D description binding site for residue SO4 C 302 source : AC4 26) chain C residue 154 type sequence V description binding site for residue SO4 C 302 source : AC4 27) chain C residue 156 type sequence H description binding site for residue SO4 C 302 source : AC4 28) chain D residue 91 type sequence H description binding site for residue DMS D 301 source : AC5 29) chain D residue 234 type sequence Y description binding site for residue DMS D 301 source : AC5 30) chain D residue 236 type sequence M description binding site for residue DMS D 301 source : AC5 31) chain D residue 237 type sequence W description binding site for residue DMS D 301 source : AC5 32) chain D residue 21 type sequence E description binding site for residue DMS D 302 source : AC6 33) chain D residue 150 type sequence R description binding site for residue DMS D 302 source : AC6 34) chain D residue 152 type sequence P description binding site for residue DMS D 302 source : AC6 35) chain D residue 153 type sequence D description binding site for residue DMS D 302 source : AC6 36) chain D residue 154 type sequence V description binding site for residue DMS D 302 source : AC6 37) chain D residue 156 type sequence H description binding site for residue DMS D 302 source : AC6 38) chain A residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 39) chain D residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 40) chain D residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 41) chain D residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 42) chain A residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 43) chain A residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 44) chain B residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 45) chain B residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 46) chain B residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 47) chain C residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 48) chain C residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 49) chain C residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1 50) chain A residue 53-58 type prosite sequence LSAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC source prosite : PS00134 51) chain A residue 189-200 type prosite sequence DTCRGDSGSPLV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DTcrGDSGSPLV source prosite : PS00135 52) chain A residue 111 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16944957 source Swiss-Prot : SWS_FT_FI3 53) chain B residue 111 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16944957 source Swiss-Prot : SWS_FT_FI3 54) chain C residue 111 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16944957 source Swiss-Prot : SWS_FT_FI3 55) chain D residue 111 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16944957 source Swiss-Prot : SWS_FT_FI3 56) chain A residue 164 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941 source Swiss-Prot : SWS_FT_FI4 57) chain B residue 164 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941 source Swiss-Prot : SWS_FT_FI4 58) chain C residue 164 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941 source Swiss-Prot : SWS_FT_FI4 59) chain D residue 164 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17330941 source Swiss-Prot : SWS_FT_FI4 60) chain A residue 36 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 61) chain D residue 36 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 62) chain D residue 240 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 63) chain A residue 240 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 64) chain B residue 36 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 65) chain B residue 240 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 66) chain C residue 36 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2 67) chain C residue 240 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links