eF-site ID 5fbi-A PDB Code 5fbi Chain A click to enlarge Title COMPLEMENT FACTOR D IN COMPLEX WITH COMPOUND 3b Classification HYDROLASE Compound Complement factor D Source Homo sapiens (Human) (CFAD_HUMAN) Sequence A:  ILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAA HCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPD SQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPG TLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHH DGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSG SRVCGNRKKPGIYTRVASYAAWIDSVLA Description Functional site 1) chain A residue 129 type sequence R description binding site for residue GOL A 301 source : AC1 2) chain A residue 130 type sequence V description binding site for residue GOL A 301 source : AC1 3) chain A residue 162 type sequence V description binding site for residue GOL A 301 source : AC1 4) chain A residue 163 type sequence L description binding site for residue GOL A 301 source : AC1 5) chain A residue 164 type sequence D description binding site for residue GOL A 301 source : AC1 6) chain A residue 165 type sequence R description binding site for residue GOL A 301 source : AC1 7) chain A residue 181 type sequence M description binding site for residue GOL A 301 source : AC1 8) chain A residue 182 type sequence C description binding site for residue GOL A 301 source : AC1 9) chain A residue 190 type sequence S description binding site for residue 5WD A 302 source : AC2 10) chain A residue 191 type sequence C description binding site for residue 5WD A 302 source : AC2 11) chain A residue 192 type sequence K description binding site for residue 5WD A 302 source : AC2 12) chain A residue 195 type sequence S description binding site for residue 5WD A 302 source : AC2 13) chain A residue 213 type sequence V description binding site for residue 5WD A 302 source : AC2 14) chain A residue 214 type sequence T description binding site for residue 5WD A 302 source : AC2 15) chain A residue 216 type sequence G description binding site for residue 5WD A 302 source : AC2 16) chain A residue 217 type sequence S description binding site for residue 5WD A 302 source : AC2 17) chain A residue 218 type sequence R description binding site for residue 5WD A 302 source : AC2 18) chain A residue 220 type sequence C description binding site for residue 5WD A 302 source : AC2 19) chain A residue 53-58 type prosite sequence LSAAHC description TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LSAAHC source prosite : PS00134 20) chain A residue 189-200 type prosite sequence DSCKGDSGGPLV description TRYPSIN_SER Serine proteases, trypsin family, serine active site. DSckGDSGGPLV source prosite : PS00135 21) chain A residue 57 type ACT_SITE sequence H description Charge relay system source Swiss-Prot : SWS_FT_FI1 22) chain A residue 102 type ACT_SITE sequence D description Charge relay system source Swiss-Prot : SWS_FT_FI1 23) chain A residue 195 type ACT_SITE sequence S description Charge relay system source Swiss-Prot : SWS_FT_FI1

Display surface Download Links