eF-site ID 5f5w-ABCDE PDB Code 5f5w Chain A, B, C, D, E click to enlarge Title Crystal structure of the alpha subunit of glycyl tRNA synthetase (GlyRS) from Aquifex aeolicus in complex with an analog of glycyl adenylate (Gly-SA) Classification LIGASE Compound Glycine--tRNA ligase alpha subunit Source (SYGA_AQUAE) Sequence A:  MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFL KVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTL GAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYN FELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE NVG B:  MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFL KVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTL GAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYN FELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE N C:  MYFQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFL KVLGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVI LKPAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTL GAWGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYG LERIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYN FELADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCS HVFNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE N D:  FQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKV LGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILK PAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGA WGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLE RIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFE LADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHV FNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE E:  FQDIIMTLHKFWAEKGCLIWQPYDVEVGAGTMNPATFLKV LGKKPWNVAYVEPSRRPQDGRYGENPNRLQHYYQFQVILK PAPRNPQEIYLESLERLGINPLEHDIRFVEDDWESPTLGA WGLGWEVWLDGMEITQFTYFQQAGGLDLDEISVEITYGLE RIAMYIQDKDSVFDIEWKEGITYGEIFKRSEWEWSKYNFE LADTDMLFQVYEMFEKESKRMVEEGLIFPAYDYLLKCSHV FNILDARGAISVQERARYIRRMNNLAREIAKLYLQVFE Description Functional site 1) chain A residue 33 type sequence T description binding site for residue G5A A 300 source : AC1 2) chain A residue 58 type sequence R description binding site for residue G5A A 300 source : AC1 3) chain A residue 61 type sequence D description binding site for residue G5A A 300 source : AC1 4) chain A residue 69 type sequence N description binding site for residue G5A A 300 source : AC1 5) chain A residue 70 type sequence R description binding site for residue G5A A 300 source : AC1 6) chain A residue 71 type sequence L description binding site for residue G5A A 300 source : AC1 7) chain A residue 74 type sequence Y description binding site for residue G5A A 300 source : AC1 8) chain A residue 76 type sequence Q description binding site for residue G5A A 300 source : AC1 9) chain A residue 115 type sequence W description binding site for residue G5A A 300 source : AC1 10) chain A residue 135 type sequence E description binding site for residue G5A A 300 source : AC1 11) chain A residue 136 type sequence I description binding site for residue G5A A 300 source : AC1 12) chain A residue 137 type sequence T description binding site for residue G5A A 300 source : AC1 13) chain A residue 138 type sequence Q description binding site for residue G5A A 300 source : AC1 14) chain A residue 156 type sequence E description binding site for residue G5A A 300 source : AC1 15) chain A residue 158 type sequence T description binding site for residue G5A A 300 source : AC1 16) chain A residue 160 type sequence G description binding site for residue G5A A 300 source : AC1 17) chain A residue 163 type sequence R description binding site for residue G5A A 300 source : AC1 18) chain B residue 33 type sequence T description binding site for residue G5A B 300 source : AC2 19) chain B residue 58 type sequence R description binding site for residue G5A B 300 source : AC2 20) chain B residue 61 type sequence D description binding site for residue G5A B 300 source : AC2 21) chain B residue 69 type sequence N description binding site for residue G5A B 300 source : AC2 22) chain B residue 70 type sequence R description binding site for residue G5A B 300 source : AC2 23) chain B residue 71 type sequence L description binding site for residue G5A B 300 source : AC2 24) chain B residue 74 type sequence Y description binding site for residue G5A B 300 source : AC2 25) chain B residue 76 type sequence Q description binding site for residue G5A B 300 source : AC2 26) chain B residue 115 type sequence W description binding site for residue G5A B 300 source : AC2 27) chain B residue 135 type sequence E description binding site for residue G5A B 300 source : AC2 28) chain B residue 136 type sequence I description binding site for residue G5A B 300 source : AC2 29) chain B residue 137 type sequence T description binding site for residue G5A B 300 source : AC2 30) chain B residue 138 type sequence Q description binding site for residue G5A B 300 source : AC2 31) chain B residue 156 type sequence E description binding site for residue G5A B 300 source : AC2 32) chain B residue 158 type sequence T description binding site for residue G5A B 300 source : AC2 33) chain B residue 160 type sequence G description binding site for residue G5A B 300 source : AC2 34) chain B residue 163 type sequence R description binding site for residue G5A B 300 source : AC2 35) chain C residue 33 type sequence T description binding site for residue G5A C 300 source : AC3 36) chain C residue 58 type sequence R description binding site for residue G5A C 300 source : AC3 37) chain C residue 61 type sequence D description binding site for residue G5A C 300 source : AC3 38) chain C residue 69 type sequence N description binding site for residue G5A C 300 source : AC3 39) chain C residue 70 type sequence R description binding site for residue G5A C 300 source : AC3 40) chain C residue 71 type sequence L description binding site for residue G5A C 300 source : AC3 41) chain C residue 74 type sequence Y description binding site for residue G5A C 300 source : AC3 42) chain C residue 76 type sequence Q description binding site for residue G5A C 300 source : AC3 43) chain C residue 115 type sequence W description binding site for residue G5A C 300 source : AC3 44) chain C residue 135 type sequence E description binding site for residue G5A C 300 source : AC3 45) chain C residue 136 type sequence I description binding site for residue G5A C 300 source : AC3 46) chain C residue 137 type sequence T description binding site for residue G5A C 300 source : AC3 47) chain C residue 138 type sequence Q description binding site for residue G5A C 300 source : AC3 48) chain C residue 156 type sequence E description binding site for residue G5A C 300 source : AC3 49) chain C residue 158 type sequence T description binding site for residue G5A C 300 source : AC3 50) chain C residue 160 type sequence G description binding site for residue G5A C 300 source : AC3 51) chain C residue 163 type sequence R description binding site for residue G5A C 300 source : AC3 52) chain D residue 33 type sequence T description binding site for residue G5A D 300 source : AC4 53) chain D residue 58 type sequence R description binding site for residue G5A D 300 source : AC4 54) chain D residue 61 type sequence D description binding site for residue G5A D 300 source : AC4 55) chain D residue 69 type sequence N description binding site for residue G5A D 300 source : AC4 56) chain D residue 70 type sequence R description binding site for residue G5A D 300 source : AC4 57) chain D residue 71 type sequence L description binding site for residue G5A D 300 source : AC4 58) chain D residue 74 type sequence Y description binding site for residue G5A D 300 source : AC4 59) chain D residue 76 type sequence Q description binding site for residue G5A D 300 source : AC4 60) chain D residue 115 type sequence W description binding site for residue G5A D 300 source : AC4 61) chain D residue 135 type sequence E description binding site for residue G5A D 300 source : AC4 62) chain D residue 136 type sequence I description binding site for residue G5A D 300 source : AC4 63) chain D residue 137 type sequence T description binding site for residue G5A D 300 source : AC4 64) chain D residue 138 type sequence Q description binding site for residue G5A D 300 source : AC4 65) chain D residue 156 type sequence E description binding site for residue G5A D 300 source : AC4 66) chain D residue 158 type sequence T description binding site for residue G5A D 300 source : AC4 67) chain D residue 160 type sequence G description binding site for residue G5A D 300 source : AC4 68) chain D residue 163 type sequence R description binding site for residue G5A D 300 source : AC4 69) chain E residue 33 type sequence T description binding site for residue G5A E 300 source : AC5 70) chain E residue 58 type sequence R description binding site for residue G5A E 300 source : AC5 71) chain E residue 61 type sequence D description binding site for residue G5A E 300 source : AC5 72) chain E residue 69 type sequence N description binding site for residue G5A E 300 source : AC5 73) chain E residue 70 type sequence R description binding site for residue G5A E 300 source : AC5 74) chain E residue 71 type sequence L description binding site for residue G5A E 300 source : AC5 75) chain E residue 74 type sequence Y description binding site for residue G5A E 300 source : AC5 76) chain E residue 76 type sequence Q description binding site for residue G5A E 300 source : AC5 77) chain E residue 115 type sequence W description binding site for residue G5A E 300 source : AC5 78) chain E residue 135 type sequence E description binding site for residue G5A E 300 source : AC5 79) chain E residue 136 type sequence I description binding site for residue G5A E 300 source : AC5 80) chain E residue 137 type sequence T description binding site for residue G5A E 300 source : AC5 81) chain E residue 138 type sequence Q description binding site for residue G5A E 300 source : AC5 82) chain E residue 156 type sequence E description binding site for residue G5A E 300 source : AC5 83) chain E residue 158 type sequence T description binding site for residue G5A E 300 source : AC5 84) chain E residue 160 type sequence G description binding site for residue G5A E 300 source : AC5 85) chain E residue 163 type sequence R description binding site for residue G5A E 300 source : AC5

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