eF-site ID 5f59-A PDB Code 5f59 Chain A click to enlarge Title The crystal structure of MLL3 SET domain Classification TRANSFERASE Compound Histone-lysine N-methyltransferase 2C Source Homo sapiens (Human) (KMT2C_HUMAN) Sequence A:  SKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTM VIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVID ATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRI QKGEELCYDYKFDKIPCHCGAVNCRKWM Description Functional site 1) chain A residue 4851 type sequence C description binding site for residue ZN A 5001 source : AC1 2) chain A residue 4899 type sequence C description binding site for residue ZN A 5001 source : AC1 3) chain A residue 4901 type sequence C description binding site for residue ZN A 5001 source : AC1 4) chain A residue 4906 type sequence C description binding site for residue ZN A 5001 source : AC1 5) chain A residue 4780 type sequence I description binding site for residue SAH A 5002 source : AC2 6) chain A residue 4781 type sequence Q description binding site for residue SAH A 5002 source : AC2 7) chain A residue 4782 type sequence G description binding site for residue SAH A 5002 source : AC2 8) chain A residue 4783 type sequence L description binding site for residue SAH A 5002 source : AC2 9) chain A residue 4822 type sequence R description binding site for residue SAH A 5002 source : AC2 10) chain A residue 4825 type sequence Y description binding site for residue SAH A 5002 source : AC2 11) chain A residue 4845 type sequence R description binding site for residue SAH A 5002 source : AC2 12) chain A residue 4846 type sequence Y description binding site for residue SAH A 5002 source : AC2 13) chain A residue 4848 type sequence N description binding site for residue SAH A 5002 source : AC2 14) chain A residue 4849 type sequence H description binding site for residue SAH A 5002 source : AC2 15) chain A residue 4886 type sequence Y description binding site for residue SAH A 5002 source : AC2 16) chain A residue 4898 type sequence P description binding site for residue SAH A 5002 source : AC2 17) chain A residue 4899 type sequence C description binding site for residue SAH A 5002 source : AC2 18) chain A residue 4900 type sequence H description binding site for residue SAH A 5002 source : AC2 19) chain A residue 4910 type sequence M description binding site for residue SAH A 5002 source : AC2 20) chain A residue 4825 type BINDING sequence Y description BINDING => ECO:0000255|PROSITE-ProRule:PRU00190 source Swiss-Prot : SWS_FT_FI1 21) chain A residue 4848 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 22) chain A residue 4851 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 23) chain A residue 4899 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 24) chain A residue 4901 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 25) chain A residue 4906 type BINDING sequence C description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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