eF-site ID 5ez6-B PDB Code 5ez6 Chain B click to enlarge Title Crystallization and preliminary X-ray crystallographic analysis of a small GTPase RhoA Classification SIGNALING PROTEIN Compound Transforming protein RhoA Source Homo sapiens (Human) (RHOA_HUMAN) Sequence B:  AAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFEN YVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVIL MCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDL RNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSA KTKDGVREVFEMATRAALQ Description Functional site 1) chain B residue 38 type sequence V description binding site for residue MG B 201 source : AC1 2) chain B residue 39 type sequence F description binding site for residue MG B 201 source : AC1 3) chain B residue 40 type sequence E description binding site for residue MG B 201 source : AC1 4) chain B residue 40 type sequence E description binding site for residue MG B 201 source : AC1 5) chain B residue 42 type sequence Y description binding site for residue MG B 201 source : AC1 6) chain B residue 12 type sequence G description binding site for residue MG B 202 source : AC2 7) chain B residue 13 type sequence D description binding site for residue MG B 202 source : AC2 8) chain B residue 83 type sequence C description binding site for residue MG B 202 source : AC2 9) chain B residue 91 type sequence S description binding site for residue MG B 202 source : AC2 10) chain B residue 99 type sequence W description binding site for residue MG B 202 source : AC2 11) chain B residue 17 type sequence G description binding site for residue MG B 203 source : AC3 12) chain B residue 161 type sequence A description binding site for residue MG B 203 source : AC3 13) chain B residue 15 type sequence A description binding site for residue GDP B 204 source : AC4 14) chain B residue 16 type sequence C description binding site for residue GDP B 204 source : AC4 15) chain B residue 17 type sequence G description binding site for residue GDP B 204 source : AC4 16) chain B residue 18 type sequence K description binding site for residue GDP B 204 source : AC4 17) chain B residue 19 type sequence T description binding site for residue GDP B 204 source : AC4 18) chain B residue 20 type sequence C description binding site for residue GDP B 204 source : AC4 19) chain B residue 61 type sequence A description binding site for residue GDP B 204 source : AC4 20) chain B residue 118 type sequence K description binding site for residue GDP B 204 source : AC4 21) chain B residue 120 type sequence D description binding site for residue GDP B 204 source : AC4 22) chain B residue 121 type sequence L description binding site for residue GDP B 204 source : AC4 23) chain B residue 160 type sequence S description binding site for residue GDP B 204 source : AC4 24) chain B residue 161 type sequence A description binding site for residue GDP B 204 source : AC4 25) chain B residue 162 type sequence K description binding site for residue GDP B 204 source : AC4 26) chain B residue 37 type CARBOHYD sequence T description (Microbial infection) O-linked (Glc) threonine; by C.difficile toxins TcdA and TcdB; alternate => ECO:0000269|PubMed:24905543, ECO:0000269|PubMed:7775453, ECO:0000269|PubMed:7777059 source Swiss-Prot : SWS_FT_FI8 27) chain B residue 135 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23871831 source Swiss-Prot : SWS_FT_FI9 28) chain B residue 117 type BINDING sequence N description BINDING => ECO:0000269|PubMed:10748207, ECO:0000269|PubMed:12777804 source Swiss-Prot : SWS_FT_FI1 29) chain B residue 12 type BINDING sequence G description BINDING => ECO:0000269|PubMed:10748207, ECO:0000269|PubMed:12777804 source Swiss-Prot : SWS_FT_FI1 30) chain B residue 59 type BINDING sequence D description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 31) chain B residue 160 type BINDING sequence S description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 32) chain B residue 30 type BINDING sequence F description BINDING => ECO:0000250|UniProtKB:P62820 source Swiss-Prot : SWS_FT_FI2 33) chain B residue 34 type MOD_RES sequence Y description (Microbial infection) O-AMP-tyrosine; by Haemophilus IbpA; alternate => ECO:0000269|PubMed:19362538 source Swiss-Prot : SWS_FT_FI3 34) chain B residue 37 type MOD_RES sequence T description (Microbial infection) O-AMP-threonine; by Vibrio VopS => ECO:0000269|PubMed:19039103 source Swiss-Prot : SWS_FT_FI4 35) chain B residue 41 type MOD_RES sequence N description (Microbial infection) ADP-ribosylasparagine; by botulinum toxin => ECO:0000305|PubMed:1328215 source Swiss-Prot : SWS_FT_FI5 36) chain B residue 63 type MOD_RES sequence Q description 5-glutamyl serotonin => ECO:0000250|UniProtKB:Q9QUI0 source Swiss-Prot : SWS_FT_FI6 37) chain B residue 34 type CARBOHYD sequence Y description (Microbial infection) O-linked (GlcNAc) tyrosine; by Photorhabdus PAU_02230; alternate => ECO:0000269|PubMed:24141704 source Swiss-Prot : SWS_FT_FI7

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