eF-site ID 5euq-B PDB Code 5euq Chain B click to enlarge Title Crystal structure of an engineered construct of phosphatidylinositol 4 kinase III beta with a potent and selective inhibitor in complex with GDP loaded Rab11 Classification Transferase/Signaling Protein Compound Ras-related protein Rab-11A Source (PI4KB_HUMAN) Sequence B:  EYDYLFKVVLIGDSGVGKSNLLSRFTRNEFNLESGVEFAT RSIQVDGKTIKAQIWDTATSAYYRGAVGALLVYDIAKHLT YENVERWLKELRDHADSNIVIMLVGNKSDLRHLRAVPTDE ARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIY Description Functional site 1) chain B residue 20 type sequence S description binding site for residue GDP B 301 source : AC1 2) chain B residue 21 type sequence G description binding site for residue GDP B 301 source : AC1 3) chain B residue 22 type sequence V description binding site for residue GDP B 301 source : AC1 4) chain B residue 23 type sequence G description binding site for residue GDP B 301 source : AC1 5) chain B residue 24 type sequence K description binding site for residue GDP B 301 source : AC1 6) chain B residue 25 type sequence S description binding site for residue GDP B 301 source : AC1 7) chain B residue 26 type sequence N description binding site for residue GDP B 301 source : AC1 8) chain B residue 36 type sequence F description binding site for residue GDP B 301 source : AC1 9) chain B residue 37 type sequence N description binding site for residue GDP B 301 source : AC1 10) chain B residue 38 type sequence L description binding site for residue GDP B 301 source : AC1 11) chain B residue 124 type sequence N description binding site for residue GDP B 301 source : AC1 12) chain B residue 125 type sequence K description binding site for residue GDP B 301 source : AC1 13) chain B residue 127 type sequence D description binding site for residue GDP B 301 source : AC1 14) chain B residue 128 type sequence L description binding site for residue GDP B 301 source : AC1 15) chain B residue 154 type sequence S description binding site for residue GDP B 301 source : AC1 16) chain B residue 155 type sequence A description binding site for residue GDP B 301 source : AC1 17) chain B residue 156 type sequence L description binding site for residue GDP B 301 source : AC1 18) chain B residue 14-27 type prosite sequence VVLIGDSGVGKSNL description SIGMA54_INTERACT_1 Sigma-54 interaction domain ATP-binding region A signature. VVLiGDSGVGKsnL source prosite : PS00675 19) chain B residue 124 type MOD_RES sequence N description Phosphoserine => ECO:0000269|PubMed:11277933, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1 20) chain B residue 154 type MOD_RES sequence S description Phosphoserine => ECO:0000269|PubMed:11277933, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 source Swiss-Prot : SWS_FT_FI1

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