|
|
eF-site ID
|
5eu7-A |
|
PDB Code
|
5eu7 |
|
Chain
|
A |
|
click to enlarge
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Title
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Crystal structure of HIV-1 integrase catalytic core in complex with Fab |
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Classification
|
VIRAL PROTEIN |
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Compound
|
Integrase |
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Source
|
Human immunodeficiency virus type 1 group M subtype B (isolate HXB2) (HIV-1) (5EU7) |
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Sequence
|
A: |
SPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQE
TAYFLLKLAGRWPVKTIHTDNGSNFTSTTVKAACDWAGIK
QEFGVESMNKELKKIIGQVRDQAEHLKTAVQMAVFIHNKK
RKGGIGGYSAGERIVDIIATDIQ
|
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Description
|
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Functional site
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|
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1)
|
chain |
A |
| residue |
152 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000305
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
2)
|
chain |
A |
| residue |
116 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
3)
|
chain |
A |
| residue |
64 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000250
|
| source |
Swiss-Prot : SWS_FT_FI1
|
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