eF-site ID 5erg-B PDB Code 5erg Chain B click to enlarge Title Crystal structure of the two-subunit tRNA m1A58 methyltransferase TRM6-TRM61 in complex with SAM Classification TRANSFERASE Compound tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 Source Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (TRM61_YEAST) Sequence B:  NCFSGYKDLIKEGDLTLIWVSRDNIKPVRMHSEEVFNTRY GSFPHKDIIGKPYGSQIAIRTFAFVHVLQPTPELWTLSLP HRTQIVYTPDSSYIMQRLNCSPHSRVIEAGTGSGSFSHAF ARSVGHLFSFEFHHIRYEQALEEFKEHGLIDDNVTITHRD VCQGGFLIKKGDTTSYEFGNNETAASLNANVVFLDLPAPW DAIPHLDSVISVDEKVGLCCFSPCIEQVDKTLDVLEKYGW TDVEMVEIQGRQYESRRQMVRSLNDALERLRDIKRHKIKE GDSNYKWKEVTKMEAEIKSHTSYLTFAFKVVNRSRDDEKV NEIL Description Functional site 1) chain B residue 92 type sequence Q description binding site for residue SAM B 401 source : AC1 2) chain B residue 94 type sequence V description binding site for residue SAM B 401 source : AC1 3) chain B residue 118 type sequence G description binding site for residue SAM B 401 source : AC1 4) chain B residue 119 type sequence T description binding site for residue SAM B 401 source : AC1 5) chain B residue 120 type sequence G description binding site for residue SAM B 401 source : AC1 6) chain B residue 121 type sequence S description binding site for residue SAM B 401 source : AC1 7) chain B residue 122 type sequence G description binding site for residue SAM B 401 source : AC1 8) chain B residue 123 type sequence S description binding site for residue SAM B 401 source : AC1 9) chain B residue 124 type sequence F description binding site for residue SAM B 401 source : AC1 10) chain B residue 139 type sequence E description binding site for residue SAM B 401 source : AC1 11) chain B residue 140 type sequence F description binding site for residue SAM B 401 source : AC1 12) chain B residue 144 type sequence R description binding site for residue SAM B 401 source : AC1 13) chain B residue 167 type sequence R description binding site for residue SAM B 401 source : AC1 14) chain B residue 168 type sequence D description binding site for residue SAM B 401 source : AC1 15) chain B residue 169 type sequence V description binding site for residue SAM B 401 source : AC1 16) chain B residue 170 type sequence C description binding site for residue SAM B 401 source : AC1 17) chain B residue 203 type sequence D description binding site for residue SAM B 401 source : AC1 18) chain B residue 204 type sequence L description binding site for residue SAM B 401 source : AC1 19) chain B residue 94 type BINDING sequence V description BINDING => ECO:0000269|PubMed:27582183, ECO:0000312|PDB:5ERG source Swiss-Prot : SWS_FT_FI1 20) chain B residue 121 type BINDING sequence S description BINDING => ECO:0000269|PubMed:27582183, ECO:0000312|PDB:5ERG source Swiss-Prot : SWS_FT_FI1 21) chain B residue 139 type BINDING sequence E description BINDING => ECO:0000269|PubMed:27582183, ECO:0000312|PDB:5ERG source Swiss-Prot : SWS_FT_FI1 22) chain B residue 168 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27582183, ECO:0000312|PDB:5ERG source Swiss-Prot : SWS_FT_FI1 23) chain B residue 203 type BINDING sequence D description BINDING => ECO:0000269|PubMed:27582183, ECO:0000312|PDB:5ERG source Swiss-Prot : SWS_FT_FI1 24) chain B residue 144 type BINDING sequence R description BINDING => ECO:0000250|UniProtKB:Q96FX7 source Swiss-Prot : SWS_FT_FI2

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