eF-site ID 5ecg-D
PDB Code 5ecg
Chain D

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Title Crystal structure of the BRCT domains of 53BP1 in complex with p53 and H2AX-pSer139 (gammaH2AX)
Classification ANTITUMOR PROTEIN
Compound Cellular tumor antigen p53
Source Homo sapiens (Human) (5ECG)
Sequence D:  RGPLPLNKTLFLGYAFLLTMATEIPPFNKQYTESQLRAGA
GYILEDFNEAQCNTAYQCLLIADQHCRTRKYFLCLASGIP
CVSHVWVHDSCHANQLQNYRNYLLPAGYSLEEQRILDWQP
RENPFQNLKVLLVSDQQQNFLELWSEILMTGGAASVKQHH
SSADIALGVFDVVVTDPSCPASVLKCAEALQLPVVSQEWV
IQCLIVGERIGFKQHPKYKHDYV
Description


Functional site

1) chain D
residue 1737
type
sequence T
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

2) chain D
residue 1738
type
sequence M
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

3) chain D
residue 1740
type
sequence T
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

4) chain D
residue 1773
type
sequence K
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

5) chain D
residue 1812
type
sequence T
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

6) chain D
residue 1814
type
sequence K
description binding site for Di-peptide SEP E 139 and GLN E 140
source : AC3

7) chain D
residue 1797
type
sequence N
description binding site for Di-peptide SEP F 139 and GLN F 140
source : AC4

8) chain D
residue 1798
type
sequence T
description binding site for Di-peptide SEP F 139 and GLN F 140
source : AC4

9) chain D
residue 1778
type MOD_RES
sequence S
description Phosphoserine => ECO:0000269|PubMed:19176521, ECO:0000269|PubMed:21144835
source Swiss-Prot : SWS_FT_FI2


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