eF-site ID 5e0u-E
PDB Code 5e0u
Chain E

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Title Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms
Classification DNA BINDING PROTEIN
Compound Proliferating cell nuclear antigen
Source Homo sapiens (Human) (CDN1A_HUMAN)
Sequence E:  RRQTSMTDFYHSKRRLIFS
Description


Functional site

1) chain E
residue 145
type MOD_RES
sequence T
description Phosphothreonine; by PKA, PKB/AKT1, PIM1 and PIM2 => ECO:0000269|PubMed:10753973, ECO:0000269|PubMed:11463845, ECO:0000269|PubMed:12431783, ECO:0000269|PubMed:16982699, ECO:0000269|PubMed:20307683
source Swiss-Prot : SWS_FT_FI1

2) chain E
residue 146
type MOD_RES
sequence S
description Phosphoserine; by PKC and NUAK1 => ECO:0000269|PubMed:10753973, ECO:0000269|PubMed:25329316
source Swiss-Prot : SWS_FT_FI2

3) chain E
residue 160
type MOD_RES
sequence S
description Phosphoserine; by PKC; in vitro => ECO:0000269|PubMed:10753973
source Swiss-Prot : SWS_FT_FI3


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