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eF-site ID
|
5e0u-A |
|
PDB Code
|
5e0u |
|
Chain
|
A |
|
click to enlarge
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Title
|
Human PCNA variant (S228I) complexed with p21 at 1.9 Angstroms |
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Classification
|
DNA BINDING PROTEIN |
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Compound
|
Proliferating cell nuclear antigen |
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Source
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Homo sapiens (Human) (CDN1A_HUMAN) |
|
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Sequence
|
A: |
MFEARLVQGSILKKVLEALKDLINEACWDISSSGVNLQSM
DSSHVSLVQLTLRSEGFDTYRCDRNLAMGVNLTSMSKILK
CAGNEDIITLRAEDNADTLALVFEAPNQEKVSDYEMKLMD
LDVEQLGIPEQEYSCVVKMPSGEFARICRDLSHIGDAVVI
SCAKDGVKFSASGELGNGNIKLSQTSNVDKEEEAVTIEMN
EPVQLTFALRYLNFFTKATPLSSTVTLIMSADVPLVVEYK
IADMGHLKYYLAPKI
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Description
|
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Functional site
|
|
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1)
|
chain |
A |
| residue |
61-79 |
| type |
prosite |
| sequence |
RCDRNLAMGVNLTSMSKIL
|
| description |
PCNA_2 Proliferating cell nuclear antigen signature 2. RCDRnlaMgvnLtSMsKIL
|
| source |
prosite : PS00293
|
|
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2)
|
chain |
A |
| residue |
34-57 |
| type |
prosite |
| sequence |
GVNLQSMDSSHVSLVQLTLRSEGF
|
| description |
PCNA_1 Proliferating cell nuclear antigen signature 1. GVnLqSMDsSHVsLVqLtLrsegF
|
| source |
prosite : PS01251
|
|
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3)
|
chain |
A |
| residue |
254 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
|
| source |
Swiss-Prot : SWS_FT_FI6
|
|
|
4)
|
chain |
A |
| residue |
211 |
| type |
MOD_RES |
| sequence |
Y
|
| description |
Phosphotyrosine; by EGFR => ECO:0000269|PubMed:17115032
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
5)
|
chain |
A |
| residue |
164 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17108083, ECO:0000269|PubMed:17130289
|
| source |
Swiss-Prot : SWS_FT_FI5
|
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