eF-site ID 5dui-A
PDB Code 5dui
Chain A

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Title Identification of a new FoxO1 binding site that precludes CREB binding at the glucose-6-phosphatase catalytic subunit gene promoter
Classification TRANSCRIPTION/dna
Compound Forkhead box protein O1
Source Homo sapiens (Human) (5DUI)
Sequence A:  WGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKD
KGDSNSSAGWKNSIRHNLSLHSKFIRVQNEGTGKSSWWML
NPEGGK
Description


Functional site

1) chain A
residue 209-215
type prosite
sequence WKNSIRH
description FORK_HEAD_2 Fork head domain signature 2. WKNSIRH
source prosite : PS00658

2) chain A
residue 212
type MOD_RES
sequence S
description Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:18786403, ECO:0000269|PubMed:19221179, ECO:0000269|PubMed:21245099
source Swiss-Prot : SWS_FT_FI3

3) chain A
residue 218
type MOD_RES
sequence S
description Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:18786403
source Swiss-Prot : SWS_FT_FI4

4) chain A
residue 234
type MOD_RES
sequence S
description Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:18786403
source Swiss-Prot : SWS_FT_FI4

5) chain A
residue 235
type MOD_RES
sequence S
description Phosphoserine; by STK4/MST1 => ECO:0000269|PubMed:18786403
source Swiss-Prot : SWS_FT_FI4

6) chain A
residue 245
type MOD_RES
sequence K
description N6-acetyllysine => ECO:0000250|UniProtKB:Q9R1E0
source Swiss-Prot : SWS_FT_FI5

7) chain A
residue 165
type SITE
sequence Y
description DNA-binding => ECO:0000269|PubMed:18786403
source Swiss-Prot : SWS_FT_FI2

8) chain A
residue 225
type SITE
sequence R
description DNA-binding => ECO:0000269|PubMed:18786403
source Swiss-Prot : SWS_FT_FI2


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