|
|
eF-site ID
|
5dqz-C |
|
PDB Code
|
5dqz |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Crystal Structure of Cas-DNA-PAM complex |
|
Classification
|
HYDROLASE/DNA |
|
Compound
|
CRISPR-associated endonuclease Cas1 |
|
Source
|
Escherichia coli (strain K12) (CAS2_ECOLI) |
|
|
Sequence
|
C: |
TWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIR
THIPVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEA
GVRVYASGQPGGARSDKLLYQAKLALDEDLRLKVVRKMFE
LRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWN
GRRYDPKGDTINQCISAATSCLYGVTEAAILAAGYAPAIG
FVHTGKPLSFVYDIADIIKFDTVVPKAFEIARRNPGEPDR
EVRLACRDIFRSSKTLAKLIPLIEDVLAAGEIQPPAPPED
AQPVAIPLPVSLGDAGHRSS
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
141 |
| type |
|
| sequence |
E
|
| description |
binding site for residue MG C 401
|
| source |
: AC1
|
|
|
2)
|
chain |
C |
| residue |
208 |
| type |
|
| sequence |
H
|
| description |
binding site for residue MG C 401
|
| source |
: AC1
|
|
|
3)
|
chain |
C |
| residue |
221 |
| type |
|
| sequence |
D
|
| description |
binding site for residue MG C 401
|
| source |
: AC1
|
|
|
4)
|
chain |
C |
| residue |
141 |
| type |
BINDING |
| sequence |
E
|
| description |
BINDING => ECO:0000269|PubMed:26503043, ECO:0007744|PDB:5DS5
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
5)
|
chain |
C |
| residue |
221 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:26503043, ECO:0007744|PDB:5DS5
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
6)
|
chain |
C |
| residue |
208 |
| type |
BINDING |
| sequence |
H
|
| description |
BINDING => ECO:0000305|PubMed:26503043
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
|