eF-site ID 5dkw-B PDB Code 5dkw Chain B click to enlarge Title Ternary crystal structure of polymerase lambda with a GA mispair at the primer terminus with Ca2+ in the active Classification TRANSFERASE/DNA Compound DNA polymerase lambda Source (5DKW) Sequence B:  ATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKS FHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHI SESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQAS LTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNS GLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLL DSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRR LDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLS EHALSTAVVGPGRVLPTPTEKDVFRLLGLPYREPAERDW Description Functional site 1) chain B residue 300 type sequence C description binding site for residue CA B 601 source : AC4 2) chain B residue 302 type sequence I description binding site for residue CA B 601 source : AC4 3) chain B residue 305 type sequence I description binding site for residue CA B 601 source : AC4 4) chain B residue 339 type sequence S description binding site for residue CA B 602 source : AC5 5) chain B residue 341 type sequence I description binding site for residue CA B 602 source : AC5 6) chain B residue 344 type sequence A description binding site for residue CA B 602 source : AC5 7) chain B residue 386 type sequence R description binding site for residue DTP B 603 source : AC6 8) chain B residue 416 type sequence G description binding site for residue DTP B 603 source : AC6 9) chain B residue 417 type sequence S description binding site for residue DTP B 603 source : AC6 10) chain B residue 420 type sequence R description binding site for residue DTP B 603 source : AC6 11) chain B residue 426 type sequence G description binding site for residue DTP B 603 source : AC6 12) chain B residue 427 type sequence D description binding site for residue DTP B 603 source : AC6 13) chain B residue 429 type sequence D description binding site for residue DTP B 603 source : AC6 14) chain B residue 505 type sequence Y description binding site for residue DTP B 603 source : AC6 15) chain B residue 506 type sequence F description binding site for residue DTP B 603 source : AC6 16) chain B residue 508 type sequence G description binding site for residue DTP B 603 source : AC6 17) chain B residue 513 type sequence N description binding site for residue DTP B 603 source : AC6 18) chain B residue 427 type sequence D description binding site for residue CA B 604 source : AC7 19) chain B residue 429 type sequence D description binding site for residue CA B 604 source : AC7 20) chain B residue 312 type ACT_SITE sequence K description Schiff-base intermediate with DNA => ECO:0000269|PubMed:11457865 source Swiss-Prot : SWS_FT_FI1 21) chain B residue 386 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 22) chain B residue 417 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 23) chain B residue 426 type BINDING sequence G description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 24) chain B residue 513 type BINDING sequence N description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 25) chain B residue 427 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3 26) chain B residue 429 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3 27) chain B residue 490 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3

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