eF-site ID 5dkh-C PDB Code 5dkh Chain C click to enlarge Title Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17 Classification TRANSCRIPTION Compound Probable global transcription activator SNF2L2 Source Homo sapiens (Human) (SMCA2_HUMAN) Sequence C:  PPKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELP EYYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHN AQTFNLEGSQIYEDSIVLQSVFKSARQKIAKEE Description Functional site 1) chain C residue 1417 type sequence E description binding site for residue EDO B 1503 source : AC6 2) chain C residue 1490 type sequence K description binding site for residue EDO B 1504 source : AC7 3) chain C residue 1491 type sequence E description binding site for residue EDO B 1504 source : AC7 4) chain C residue 1441 type sequence H description binding site for residue ZN C 1501 source : AC9 5) chain C residue 1458 type sequence H description binding site for residue ZN C 1501 source : AC9 6) chain C residue 1441 type sequence H description binding site for residue ZN C 1502 source : AD1 7) chain C residue 1458 type sequence H description binding site for residue ZN C 1502 source : AD1

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