eF-site ID 5dkh-B PDB Code 5dkh Chain B click to enlarge Title Crystal structure of the bromodomain of human BRM (SMARCA2) in complex with a hydroxyphenyl propenone inhibitor 17 Classification TRANSCRIPTION Compound Probable global transcription activator SNF2L2 Source Homo sapiens (Human) (SMCA2_HUMAN) Sequence B:  PKLTKQMNAIIDTVINYKDSSGRQLSEVFIQLPSRKELPE YYELIRKPVDFKKIKERIRNHKYRSLGDLEKDVMLLCHNA QTFNLEGSQIYEDSIVLQSVFKSARQKIAK Description Functional site 1) chain B residue 1441 type sequence H description binding site for residue ZN B 1501 source : AC4 2) chain B residue 1458 type sequence H description binding site for residue ZN B 1501 source : AC4 3) chain B residue 1441 type sequence H description binding site for residue ZN B 1502 source : AC5 4) chain B residue 1458 type sequence H description binding site for residue ZN B 1502 source : AC5 5) chain B residue 1467 type sequence G description binding site for residue EDO B 1503 source : AC6 6) chain B residue 1472 type sequence E description binding site for residue EDO B 1503 source : AC6 7) chain B residue 1417 type sequence E description binding site for residue EDO B 1504 source : AC7 8) chain B residue 1408 type sequence V description binding site for residue 5C0 B 1505 source : AC8 9) chain B residue 1409 type sequence F description binding site for residue 5C0 B 1505 source : AC8 10) chain B residue 1412 type sequence L description binding site for residue 5C0 B 1505 source : AC8 11) chain B residue 1421 type sequence Y description binding site for residue 5C0 B 1505 source : AC8 12) chain B residue 1429 type sequence V description binding site for residue 5C0 B 1505 source : AC8 13) chain B residue 1460 type sequence A description binding site for residue 5C0 B 1505 source : AC8 14) chain B residue 1464 type sequence N description binding site for residue 5C0 B 1505 source : AC8 15) chain B residue 1470 type sequence I description binding site for residue 5C0 B 1505 source : AC8

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