eF-site ID 5ddy-C PDB Code 5ddy Chain C click to enlarge Title Binary complex of human Polymerase lambda with dCTP Classification TRANSFERASE Compound DNA polymerase lambda Source Homo sapiens (Human) (DPOLL_HUMAN) Sequence C:  ATNHNLHITEKLEVLAKAYSVQGDKWRALGYAKAINALKS FHKPVTSYQEACSIPGIGKRMAEKIIEILESGHLRKLDHI SESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQAS LTTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNS GLLCVACGSYRRGKATCGDVDVLITHPDGRSHRGIFSRLL DSLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRR LDIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLS EHALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYR EPAERDW Description Functional site 1) chain C residue 416 type sequence G description binding site for residue MG C 601 source : AC5 2) chain C residue 417 type sequence S description binding site for residue MG C 601 source : AC5 3) chain C residue 427 type sequence D description binding site for residue MG C 601 source : AC5 4) chain C residue 429 type sequence D description binding site for residue MG C 601 source : AC5 5) chain C residue 427 type sequence D description binding site for residue MN C 602 source : AC6 6) chain C residue 429 type sequence D description binding site for residue MN C 602 source : AC6 7) chain C residue 490 type sequence D description binding site for residue MN C 602 source : AC6 8) chain C residue 386 type sequence R description binding site for residue DCP C 603 source : AC7 9) chain C residue 416 type sequence G description binding site for residue DCP C 603 source : AC7 10) chain C residue 417 type sequence S description binding site for residue DCP C 603 source : AC7 11) chain C residue 420 type sequence R description binding site for residue DCP C 603 source : AC7 12) chain C residue 426 type sequence G description binding site for residue DCP C 603 source : AC7 13) chain C residue 427 type sequence D description binding site for residue DCP C 603 source : AC7 14) chain C residue 429 type sequence D description binding site for residue DCP C 603 source : AC7 15) chain C residue 505 type sequence Y description binding site for residue DCP C 603 source : AC7 16) chain C residue 506 type sequence F description binding site for residue DCP C 603 source : AC7 17) chain C residue 508 type sequence G description binding site for residue DCP C 603 source : AC7 18) chain C residue 513 type sequence N description binding site for residue DCP C 603 source : AC7 19) chain C residue 339 type sequence S description binding site for residue MN C 604 source : AC8 20) chain C residue 312 type ACT_SITE sequence K description Schiff-base intermediate with DNA => ECO:0000269|PubMed:11457865 source Swiss-Prot : SWS_FT_FI1 21) chain C residue 386 type BINDING sequence R description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 22) chain C residue 417 type BINDING sequence S description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 23) chain C residue 426 type BINDING sequence G description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 24) chain C residue 513 type BINDING sequence N description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI2 25) chain C residue 427 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3 26) chain C residue 429 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3 27) chain C residue 490 type BINDING sequence D description BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ source Swiss-Prot : SWS_FT_FI3

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