|
|
eF-site ID
|
5d6w-C |
|
PDB Code
|
5d6w |
|
Chain
|
C |
|
click to enlarge
|
|
|
Title
|
Crystal structure of double tudor domain of human lysine demethylase KDM4A |
|
Classification
|
OXIDOREDUCTASE |
|
Compound
|
Lysine-specific demethylase 4A |
|
Source
|
(KDM4A_HUMAN) |
|
|
Sequence
|
C: |
QSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGS
FSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAK
FVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELP
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
C |
| residue |
910 |
| type |
|
| sequence |
K
|
| description |
binding site for residue SRT C 1101
|
| source |
: AC3
|
|
|
2)
|
chain |
C |
| residue |
992 |
| type |
|
| sequence |
D
|
| description |
binding site for residue SRT C 1101
|
| source |
: AC3
|
|
|
3)
|
chain |
C |
| residue |
993 |
| type |
|
| sequence |
G
|
| description |
binding site for residue SRT C 1101
|
| source |
: AC3
|
|
|
4)
|
chain |
C |
| residue |
994 |
| type |
|
| sequence |
S
|
| description |
binding site for residue SRT C 1101
|
| source |
: AC3
|
|
|
5)
|
chain |
C |
| residue |
995 |
| type |
|
| sequence |
Q
|
| description |
binding site for residue SRT C 1101
|
| source |
: AC3
|
|
|
6)
|
chain |
C |
| residue |
945 |
| type |
SITE |
| sequence |
D
|
| description |
Histone H3K4me3 binding
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
7)
|
chain |
C |
| residue |
967 |
| type |
SITE |
| sequence |
W
|
| description |
Histone H3K4me3 binding
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
8)
|
chain |
C |
| residue |
973 |
| type |
SITE |
| sequence |
Y
|
| description |
Histone H3K4me3 binding
|
| source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|