|
eF-site ID
|
5d6w-B |
PDB Code
|
5d6w |
Chain
|
B |
|
click to enlarge
|
|
Title
|
Crystal structure of double tudor domain of human lysine demethylase KDM4A |
Classification
|
OXIDOREDUCTASE |
Compound
|
Lysine-specific demethylase 4A |
Source
|
(KDM4A_HUMAN) |
|
Sequence
|
B: |
QSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGS
FSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAK
FVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELP
|
|
Description
|
|
Functional site
|
|
1)
|
chain |
B |
residue |
910 |
type |
|
sequence |
K
|
description |
binding site for residue SRT B 1101
|
source |
: AC2
|
|
2)
|
chain |
B |
residue |
993 |
type |
|
sequence |
G
|
description |
binding site for residue SRT B 1101
|
source |
: AC2
|
|
3)
|
chain |
B |
residue |
994 |
type |
|
sequence |
S
|
description |
binding site for residue SRT B 1101
|
source |
: AC2
|
|
4)
|
chain |
B |
residue |
995 |
type |
|
sequence |
Q
|
description |
binding site for residue SRT B 1101
|
source |
: AC2
|
|
5)
|
chain |
B |
residue |
945 |
type |
SITE |
sequence |
D
|
description |
Histone H3K4me3 binding
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
6)
|
chain |
B |
residue |
967 |
type |
SITE |
sequence |
W
|
description |
Histone H3K4me3 binding
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
7)
|
chain |
B |
residue |
973 |
type |
SITE |
sequence |
Y
|
description |
Histone H3K4me3 binding
|
source |
Swiss-Prot : SWS_FT_FI1
|
|
|
|