eF-site ID 5cz8-E PDB Code 5cz8 Chain E click to enlarge Title Yeast 20S proteasome beta5-L(-49)S-K33A mutant in complex with Carfilzomib Classification HYDROLASE/HYDROLASE INHIBITOR Compound Proteasome subunit alpha type-2 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence E:  NNYDGDTVTFSPTGRLFQVEYALEAIKQGSVTVGLRSNTH AVLVALKRNADELSSYQKKIIKCDEHMGLSLAGLAPDARV LSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSY GGRPYGVGLLIIGYDKSGAHLLEFQPSGNVTELYGTAIGA RSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQSLRD ESLTVDNLSIAIVGKDTPFTIYDGEAVAKYI Description Functional site 1) chain E residue 5-27 type prosite sequence YDGDTVTFSPTGRLFQVEYALEA description PROTEASOME_ALPHA_1 Proteasome alpha-type subunits signature. YdlsnSvFSPdGRnfQVEYAvkA source prosite : PS00388

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