|
|
eF-site ID
|
5cwr-CDEFPT |
|
PDB Code
|
5cwr |
|
Chain
|
C, D, E, F, P, T |
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click to enlarge
|
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Title
|
Crystal Structure of human DNA polymerase lambda L431A mutant in complex with a one nucleotide DNA gap and dCTP |
|
Classification
|
TRANSFERASE/DNA |
|
Compound
|
DNA polymerase lambda |
|
Source
|
Homo sapiens (Human) (5CWR) |
|
|
Sequence
|
C: |
GCCG
|
| D: |
GCCG
|
| E: |
CAGTAC
|
| F: |
CGGCGGTACTG
|
| P: |
CAGTAC
|
| T: |
CGGCGGTACTG
|
|
|
Description
|
|
Functional site
|
|
|
1)
|
chain |
P |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
binding site for residue DCP A 601
|
| source |
: AC1
|
|
|
2)
|
chain |
T |
| residue |
5 |
| type |
|
| sequence |
G
|
| description |
binding site for residue DCP A 601
|
| source |
: AC1
|
|
|
3)
|
chain |
P |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
binding site for residue CA A 602
|
| source |
: AC2
|
|
|
4)
|
chain |
E |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
binding site for residue DCP B 601
|
| source |
: AC4
|
|
|
5)
|
chain |
F |
| residue |
5 |
| type |
|
| sequence |
G
|
| description |
binding site for residue DCP B 601
|
| source |
: AC4
|
|
|
6)
|
chain |
E |
| residue |
6 |
| type |
|
| sequence |
C
|
| description |
binding site for residue CA B 602
|
| source |
: AC5
|
|
|
|