eF-site ID 5cw8-AB PDB Code 5cw8 Chain A, B click to enlarge Title Crystal structure of Mycobacterium tuberculosis KstR in complex with 3-oxo-4-cholesten-26-oyl-CoA Classification Transcription regulator Compound HTH-type transcriptional repressor KstR Source (KSTR_MYCTU) Sequence A:  EAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAVG TLYRYFPSKVHLLVSALGREFSRIDAAGATPFQRLNFMVG KLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEKLIDS MFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTRRASA TDVSKRLDLAVRLLIG B:  SEAQRERRKRILDATMAIASKGGYEAVQMRAVADRADVAV GTLYRYFPSKVHLLVSALGREFSRIDAKAVAGATPFQRLN FMVGKLNRAMQRNPLLTEAMTRAYVFADASAASEVDQVEK LIDSMFARAMANGEPTEDQYHIARVISDVWLSNLLAWLTR RASATDVSKRLDLAVRLLIGD Description Functional site 1) chain A residue 71 type sequence E description binding site for residue 55X A 201 source : AC1 2) chain A residue 72 type sequence F description binding site for residue 55X A 201 source : AC1 3) chain A residue 100 type sequence L description binding site for residue 55X A 201 source : AC1 4) chain A residue 103 type sequence A description binding site for residue 55X A 201 source : AC1 5) chain A residue 104 type sequence M description binding site for residue 55X A 201 source : AC1 6) chain A residue 107 type sequence N description binding site for residue 55X A 201 source : AC1 7) chain A residue 114 type sequence M description binding site for residue 55X A 201 source : AC1 8) chain A residue 118 type sequence Y description binding site for residue 55X A 201 source : AC1 9) chain A residue 158 type sequence R description binding site for residue 55X A 201 source : AC1 10) chain A residue 161 type sequence S description binding site for residue 55X A 201 source : AC1 11) chain A residue 164 type sequence W description binding site for residue 55X A 201 source : AC1 12) chain B residue 111 type sequence T description binding site for residue 55X B 201 source : AC2 13) chain B residue 136 type sequence I description binding site for residue 55X B 201 source : AC2 14) chain B residue 158 type sequence R description binding site for residue 55X B 201 source : AC2 15) chain B residue 161 type sequence S description binding site for residue 55X B 201 source : AC2 16) chain B residue 164 type sequence W description binding site for residue 55X B 201 source : AC2 17) chain A residue 148 type sequence E description binding site for residue PGE B 202 source : AC3 18) chain A residue 149 type sequence P description binding site for residue PGE B 202 source : AC3 19) chain A residue 154 type sequence Y description binding site for residue PGE B 202 source : AC3 20) chain B residue 108 type sequence P description binding site for residue PGE B 202 source : AC3 21) chain B residue 171 type sequence W description binding site for residue PGE B 202 source : AC3 22) chain B residue 172 type sequence L description binding site for residue PGE B 202 source : AC3 23) chain B residue 174 type sequence R description binding site for residue PGE B 202 source : AC3 24) chain A residue 38-57 type DNA_BIND sequence QMRAVADRADVAVGTLYRYF description H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335 source Swiss-Prot : SWS_FT_FI1 25) chain B residue 38-57 type DNA_BIND sequence QMRAVADRADVAVGTLYRYF description H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00335 source Swiss-Prot : SWS_FT_FI1

Display surface Download Links