eF-site ID 5cuq-B PDB Code 5cuq Chain B click to enlarge Title Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase Classification Viral protein/Inhibitor Compound Nonstructural protein NS5 Source (C0LMU0_9FLAV) Sequence B:  GETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGL KRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRG GWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVK LMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVL KMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLV RNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMT HRRPTIEKDVDLGAGTR Description Functional site 1) chain B residue 81 type sequence G description binding site for residue NSC B 301 source : AC2 2) chain B residue 104 type sequence T description binding site for residue NSC B 301 source : AC2 3) chain B residue 105 type sequence K description binding site for residue NSC B 301 source : AC2 4) chain B residue 109 type sequence G description binding site for residue NSC B 301 source : AC2 5) chain B residue 110 type sequence H description binding site for residue NSC B 301 source : AC2 6) chain B residue 111 type sequence E description binding site for residue NSC B 301 source : AC2 7) chain B residue 131 type sequence D description binding site for residue NSC B 301 source : AC2 8) chain B residue 132 type sequence V description binding site for residue NSC B 301 source : AC2 9) chain B residue 133 type sequence F description binding site for residue NSC B 301 source : AC2

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