eF-site ID 5cuq-A PDB Code 5cuq Chain A click to enlarge Title Identification and characterization of novel broad spectrum inhibitors of the flavivirus methyltransferase Classification Viral protein/Inhibitor Compound Nonstructural protein NS5 Source (C0LMU0_9FLAV) Sequence A:  GETLGEKWKKKLNQLSRKEFDLYKKSGITEVDRTEAKEGL KRGETTHHAVSRGSAKLQWFVERNMVIPEGRVIDLGCGRG GWSYYCAGLKKVTEVRGYTKGGPGHEEPVPMSTYGWNIVK LMSGKDVFYLPPEKCDTLLCDIGESSPSPTVEESRTIRVL KMVEPWLKNNQFCIKVLNPYMPTVIEHLERLQRKHGGMLV RNPLSRNSTHEMYWISNGTGNIVSSVNMVSRLLLNRFTMT HRRPTIEKDVDLGAGTR Description Functional site 1) chain A residue 81 type sequence G description binding site for residue NSC A 301 source : AC1 2) chain A residue 109 type sequence G description binding site for residue NSC A 301 source : AC1 3) chain A residue 110 type sequence H description binding site for residue NSC A 301 source : AC1 4) chain A residue 111 type sequence E description binding site for residue NSC A 301 source : AC1 5) chain A residue 130 type sequence K description binding site for residue NSC A 301 source : AC1 6) chain A residue 131 type sequence D description binding site for residue NSC A 301 source : AC1 7) chain A residue 132 type sequence V description binding site for residue NSC A 301 source : AC1 8) chain A residue 133 type sequence F description binding site for residue NSC A 301 source : AC1 9) chain A residue 147 type sequence I description binding site for residue NSC A 301 source : AC1

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