|
|
eF-site ID
|
5cp6-D |
|
PDB Code
|
5cp6 |
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Chain
|
D |
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click to enlarge
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Title
|
Nucleosome Core Particle with Adducts from the Anticancer Compound, [(eta6-5,8,9,10-tetrahydroanthracene)Ru(ethylenediamine)Cl][PF6] |
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Classification
|
STRUCTURAL PROTEIN/DNA |
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Compound
|
DNA (145-MER) |
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Source
|
Xenopus laevis (African clawed frog) (H2B11_XENLA) |
|
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Sequence
|
D: |
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVF
ERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHA
VSEGTKAVTKYTSAK
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
D |
| residue |
122 |
| type |
|
| sequence |
K
|
| description |
binding site for residue RUH J 102
|
| source |
: AC3
|
|
|
2)
|
chain |
D |
| residue |
87 |
| type |
|
| sequence |
T
|
| description |
binding site for residue SO4 D 201
|
| source |
: AC4
|
|
|
3)
|
chain |
D |
| residue |
88 |
| type |
|
| sequence |
S
|
| description |
binding site for residue SO4 D 201
|
| source |
: AC4
|
|
|
4)
|
chain |
D |
| residue |
45 |
| type |
|
| sequence |
V
|
| description |
binding site for residue MG E 201
|
| source |
: AC5
|
|
|
5)
|
chain |
D |
| residue |
89-111 |
| type |
prosite |
| sequence |
REIQTAVRLLLPGELAKHAVSEG
|
| description |
HISTONE_H2B Histone H2B signature. REIQTavRlLLpGELaKHAVSEG
|
| source |
prosite : PS00357
|
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