|
|
eF-site ID
|
5chg-A |
|
PDB Code
|
5chg |
|
Chain
|
A |
|
click to enlarge
|
|
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Title
|
Human DNA polymerase lambda L431A mutant- MgdGTP binary and complex with 6 paired DNA |
|
Classification
|
TRANSFERASE/DNA |
|
Compound
|
DNA polymerase lambda |
|
Source
|
Homo sapiens (Human) (5CHG) |
|
|
Sequence
|
A: |
ESVPVLELFSNIWGAGTKTAQMWYQQGFRSLEDIRSQASL
TTQQAIGLKHYSDFLERMPREEATEIEQTVQKAAQAFNSG
LLCVACGSYRRGKATCGDVDVAITHPDGRSHRGIFSRLLD
SLRQEGFLTDDLVSQEENGQQQKYLGVCRLPGPGRRHRRL
DIIVVPYSEFACALLYFTGSAHFNRSMRALAKTKGMSLSE
HALSTAVVRNTHGCKVGPGRVLPTPTEKDVFRLLGLPYRE
PAERDW
|
|
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Description
|
|
Functional site
|
|
|
1)
|
chain |
A |
| residue |
339 |
| type |
|
| sequence |
S
|
| description |
binding site for residue MG A 601
|
| source |
: AC1
|
|
|
2)
|
chain |
A |
| residue |
341 |
| type |
|
| sequence |
I
|
| description |
binding site for residue MG A 601
|
| source |
: AC1
|
|
|
3)
|
chain |
A |
| residue |
344 |
| type |
|
| sequence |
A
|
| description |
binding site for residue MG A 601
|
| source |
: AC1
|
|
|
4)
|
chain |
A |
| residue |
386 |
| type |
BINDING |
| sequence |
R
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
5)
|
chain |
A |
| residue |
417 |
| type |
BINDING |
| sequence |
S
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
6)
|
chain |
A |
| residue |
426 |
| type |
BINDING |
| sequence |
G
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
7)
|
chain |
A |
| residue |
513 |
| type |
BINDING |
| sequence |
N
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI2
|
|
|
8)
|
chain |
A |
| residue |
427 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
9)
|
chain |
A |
| residue |
429 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
10)
|
chain |
A |
| residue |
490 |
| type |
BINDING |
| sequence |
D
|
| description |
BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
|