eF-site/Summary 5caw-A

eF-site ID	5caw-A
PDB Code	5caw
Chain	A

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Title	Structure of Pediculus humanus Parkin bound to phospho-ubiquitin
Classification	SIGNALING PROTEIN
Compound	E3 ubiquitin-protein ligase parkin
Source	Pediculus humanus subsp. corporis (Body louse) (UBB_HUMAN)

Sequence	A:	NKAHFFIYCANPCKKINTGKLRVCCSECKHGAFTVDTDPQ SWADVLDKNKITGVCNNVGCEGLYAKFYFKCASHPSQGEN DTAVPLNLIKRNHKKIPCLACTDICDPVLVFSCDNRHVTC LECFKNYCGSRLKDRQFLSHPDFGYTLPCPAGCSNSFIEE VHHFRLLTDAQYEQYHRFATEEFILQAGGVLCPQPGCGQG ILIDQNCNRVQCSCGYVFCGKCLEGFHLGECLNPLDPEKL EKARWDVLTKPCPKCRTSTERAGGCMHMICTRANCGFHWC WVCQGPWERDCMASHWFG

Description

Functional site


1)	chain	A
	residue	151
	type
	sequence	C
	description	binding site for residue ZN A 1001
	source	: AC1

2)	chain	A
	residue	155
	type
	sequence	C
	description	binding site for residue ZN A 1001
	source	: AC1

3)	chain	A
	residue	213
	type
	sequence	C
	description	binding site for residue ZN A 1001
	source	: AC1

4)	chain	A
	residue	216
	type
	sequence	H
	description	binding site for residue ZN A 1001
	source	: AC1

5)	chain	A
	residue	167
	type
	sequence	C
	description	binding site for residue ZN A 1002
	source	: AC2

6)	chain	A
	residue	170
	type
	sequence	C
	description	binding site for residue ZN A 1002
	source	: AC2

7)	chain	A
	residue	197
	type
	sequence	C
	description	binding site for residue ZN A 1002
	source	: AC2

8)	chain	A
	residue	202
	type
	sequence	C
	description	binding site for residue ZN A 1002
	source	: AC2

9)	chain	A
	residue	240
	type
	sequence	C
	description	binding site for residue ZN A 1003
	source	: AC3

10)	chain	A
	residue	243
	type
	sequence	C
	description	binding site for residue ZN A 1003
	source	: AC3

11)	chain	A
	residue	262
	type
	sequence	C
	description	binding site for residue ZN A 1003
	source	: AC3

12)	chain	A
	residue	265
	type
	sequence	C
	description	binding site for residue ZN A 1003
	source	: AC3

13)	chain	A
	residue	255
	type
	sequence	C
	description	binding site for residue ZN A 1004
	source	: AC4

14)	chain	A
	residue	259
	type
	sequence	H
	description	binding site for residue ZN A 1004
	source	: AC4

15)	chain	A
	residue	291
	type
	sequence	C
	description	binding site for residue ZN A 1004
	source	: AC4

16)	chain	A
	residue	295
	type
	sequence	C
	description	binding site for residue ZN A 1004
	source	: AC4

17)	chain	A
	residue	334
	type
	sequence	C
	description	binding site for residue ZN A 1005
	source	: AC5

18)	chain	A
	residue	339
	type
	sequence	C
	description	binding site for residue ZN A 1005
	source	: AC5

19)	chain	A
	residue	354
	type
	sequence	C
	description	binding site for residue ZN A 1005
	source	: AC5

20)	chain	A
	residue	356
	type
	sequence	C
	description	binding site for residue ZN A 1005
	source	: AC5

21)	chain	A
	residue	361
	type
	sequence	C
	description	binding site for residue ZN A 1006
	source	: AC6

22)	chain	A
	residue	364
	type
	sequence	C
	description	binding site for residue ZN A 1006
	source	: AC6

23)	chain	A
	residue	369
	type
	sequence	H
	description	binding site for residue ZN A 1006
	source	: AC6

24)	chain	A
	residue	373
	type
	sequence	C
	description	binding site for residue ZN A 1006
	source	: AC6

25)	chain	A
	residue	415
	type
	sequence	C
	description	binding site for residue ZN A 1007
	source	: AC7

26)	chain	A
	residue	418
	type
	sequence	C
	description	binding site for residue ZN A 1007
	source	: AC7

27)	chain	A
	residue	433
	type
	sequence	C
	description	binding site for residue ZN A 1007
	source	: AC7

28)	chain	A
	residue	438
	type
	sequence	C
	description	binding site for residue ZN A 1007
	source	: AC7

29)	chain	A
	residue	443
	type
	sequence	C
	description	binding site for residue ZN A 1008
	source	: AC8

30)	chain	A
	residue	446
	type
	sequence	C
	description	binding site for residue ZN A 1008
	source	: AC8

31)	chain	A
	residue	454
	type
	sequence	C
	description	binding site for residue ZN A 1008
	source	: AC8

32)	chain	A
	residue	458
	type
	sequence	H
	description	binding site for residue ZN A 1008
	source	: AC8

33)	chain	A
	residue	183
	type
	sequence	S
	description	binding site for residue SO4 A 1009
	source	: AC9

34)	chain	A
	residue	184
	type
	sequence	W
	description	binding site for residue SO4 A 1009
	source	: AC9

35)	chain	A
	residue	258
	type
	sequence	R
	description	binding site for residue SO4 A 1009
	source	: AC9

36)	chain	A
	residue	441
	type
	sequence	H
	description	binding site for residue SO4 C 1010
	source	: AE1

37)	chain	A
	residue	449
	type
	sequence	P
	description	binding site for residue SO4 C 1010
	source	: AE1

38)	chain	A
	residue	151
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

39)	chain	A
	residue	446
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

40)	chain	A
	residue	454
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

41)	chain	A
	residue	458
	type	CROSSLNK
	sequence	H
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

42)	chain	A
	residue	167
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

43)	chain	A
	residue	197
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

44)	chain	A
	residue	202
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

45)	chain	A
	residue	213
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

46)	chain	A
	residue	216
	type	CROSSLNK
	sequence	H
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

47)	chain	A
	residue	443
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
	source	Swiss-Prot : SWS_FT_FI7

48)	chain	A
	residue	339
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

49)	chain	A
	residue	354
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

50)	chain	A
	residue	356
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

51)	chain	A
	residue	361
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

52)	chain	A
	residue	364
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

53)	chain	A
	residue	369
	type	CROSSLNK
	sequence	H
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

54)	chain	A
	residue	373
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

55)	chain	A
	residue	415
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

56)	chain	A
	residue	418
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

57)	chain	A
	residue	433
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

58)	chain	A
	residue	438
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

59)	chain	A
	residue	262
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

60)	chain	A
	residue	265
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

61)	chain	A
	residue	291
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

62)	chain	A
	residue	295
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

63)	chain	A
	residue	334
	type	CROSSLNK
	sequence	C
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269\|PubMed:16443603, ECO:0000269\|PubMed:16543144
	source	Swiss-Prot : SWS_FT_FI8

64)	chain	A
	residue	314
	type	CROSSLNK
	sequence	Y
	description	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305\|PubMed:15466860
	source	Swiss-Prot : SWS_FT_FI9