eF-site ID 5c4a-B PDB Code 5c4a Chain B click to enlarge Title Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble Classification TRANSFERASE/RNA/DNA Compound DNA-directed RNA polymerase II subunit RPB1 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence B:  DESAPITAEDSWAVISAFFREKGLVSQQLDSFNQFVDYTL QDIICEDSTLILEQLAQHTTESDNISRKYEISFGKIYVTK PMVNESDGVTHALYPQEARLRNLTYSSGLFVDVKTYEAID VPGRELKYEDSESGKVFIGRLPIMLRSKNCYLSEATESDL YKLKECPFDMGGYFIINGSEKVLIAQERSAGNIVQVFKKA APSPISHVAEIRSALEKGSRFISTLQVKLYGRSSARTIKA TLPYIKQDIPIVIIFRALGIIPDGEILEHICYDVNDWQML EMLKPCVEDGFVIQDRETALDFIGRRGTALGIKKEKRIQY AKDILQKEFLPHITQLEGFESRKAFFLGYMINRLLLCALD RKDQDDRDHFGKKRLDLAGPLLAQLFKTLFKKLTKDIFRY MQRTVEEAHDFNMKLAINAKTITSGLKYALATGNWGEQKK AMSSRAGVSQVLNRYTYSSTLSHLRRTNTPIGAKPRQLHN THWGLVCPAETPEGQACGLVKNLSLMSCISVGTDPMPIIT FLSEWGMEPLEDYVPHQSPDATRVFVNGVWHGVHRNPARL METLRTLRRKGDINPEVSMIRDIREKELKIFTDAGRVYRP LFIVEDDESLGHKELKVRKGHIAKLMATEYQDEYTWSSLL NEGLVEYIDAEEEESILIAMQPEDLEPAAKRIRATTFTHC EIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVF LTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQ NAIVAIACYSGYNQEDSMIMNQSSIDRGLFRSLFFRSYMD QEKKYGMSITETFEKPQRTNTLRMKHGTYDKLDDDGLIAP GVRVSGEDVIIGKTTPISPDEEELGQRTAYHSKRDASTPL RSTENGIVDQVLVTTNQDGLKFVKVRVRTTKIPQIGDKFA SRHGQKGTIGITYRREDMPFTAEGIVPDLIINPHAIPSRM TVAHLIECLLSKVAALSGNEGDASPFTDITVEGISKLLRE HGYQSRGFEVMYNGHTGKKLMAQIFFGPTYYQRLRHMVDD KIHARARGPMQVLTRQPVEGRSRDGGLRFGEMERDCMIAH GAASFLKERLMEASDAFRVHICGICGLMTVIAKLNHNQFE CKGCDNKIDIYQIHIPYAAKLLFQELMAMNITPRLYTDRS RD Description Functional site 1) chain B residue 1163 type sequence C description binding site for residue ZN B 1301 source : AC5 2) chain B residue 1166 type sequence C description binding site for residue ZN B 1301 source : AC5 3) chain B residue 1170 type sequence T description binding site for residue ZN B 1301 source : AC5 4) chain B residue 1182 type sequence C description binding site for residue ZN B 1301 source : AC5 5) chain B residue 1185 type sequence C description binding site for residue ZN B 1301 source : AC5 6) chain B residue 837 type catalytic sequence D description 788 source MCSA : MCSA1 7) chain B residue 977-989 type prosite sequence GDKFASRHGQKGT description RNA_POL_BETA RNA polymerases beta chain signature. GdKFASrHGQKGT source prosite : PS01166 8) chain B residue 1166 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 9) chain B residue 1182 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 10) chain B residue 1185 type MOD_RES sequence C description Phosphothreonine => ECO:0007744|PubMed:19779198 source Swiss-Prot : SWS_FT_FI2 11) chain B residue 919 type MOD_RES sequence S description Phosphoserine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956 source Swiss-Prot : SWS_FT_FI3

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