eF-site ID 5c44-A PDB Code 5c44 Chain A click to enlarge Title Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble Classification TRANSFERASE/DNA/RNA Compound DNA-directed RNA polymerase II subunit RPB1 Source ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); Sequence A:  VGQQYSSAPLRTVKEVQFGLFSPEEVRAISVAKIRFPETM DETQTRAKIGGLNDPRLGSIDRNLKCQTCQEGMNECPGHF GHIDLAKPVFHVGFIAKIKKVCECVCMHCGKLLLDEHNEL MRQALAIKDSKKRFAAIWTLCKTKMVCETDVPSEDDPTQL VSRGGCGNTQPTIRKDGLKLVGSWKKDRATGDADEPELRV LSTEEILNIFKHISVKDFTSLGFNEVFSRPEWMILTCLPV PPPPVRPSISFNESQRGEDDLTFKLADILKANISLETLEH NGAPHHAIEEAESLLQFHVATYMDNDIAGQPQALQKSGRP VKSIRARLKGKEGRIRGNLMGKRVDFSARTVISGDPNLEL DQVGVPKSIAKTLTYPEVVTPYNIDRLTQLVRNGPNEHPG AKYVIRDSGDRIDLRYSKRAGDIQLQYGWKVERHIMDNDP VLFNRQPSLHKMSMMAHRVKVIPYSTFRLNLSVTSPYNAD FDGDEMNLHVPQSEETRAELSQLCAVPLQIVSPQSNKPCM GIVQDTLCGIRKLTLRDTFIELDQVLNMLYWVPDWDGVIP TPAIIKPKPLWSGKQILSVAIPNGIHLQRFDEGTTLLSPK DNGMLIIDGQIIFGVVEKKTVGSSNGGLIHVVTREKGPQV CAKLFGNIQKVVNFWLLHNGFSTGIGDTIADGPTMREITE TIAEAKKKVLDVTKEAQANLLTAKHGMTLRESFEDNVVRF LNEARDKAGRLAEVNLKDLNNVKQMVMAGSKGSFINIAQM SACVGQQSVEGKRIAFGFVDRTLPHFSKDDYSPESKGFVE NSYLRGLTPQEFFFHAMGGREGLIDTAVKTAETGYIQRRL VKALEDIMVHYDNTTRNSLGNVIQFIYGEDGMDAAHIEKQ SLDTIGGSDAAFEKRYRVDLLNTDHTLDPSLLESGSEILG DLKLQVLLDEEYKQLVKDRKFLREVFVDGEANWPLPVNIR RIIQNAQQTFHIDHTKPSDLTIKDIVLGVKDLQENLLVLR GKNEIIQNAQRDAVTLFCCLLRSRLATRRVLQEYRLTKQA FDWVLSNIEAQFLRSVVHPGEMVGVLAAQSIGEPATQMTL FHFAGVASKKVTSGVPRLKEILNVAKNMKTPSLTVYLEPG HAADQEQAKLIRSAIEHTTLKSVTIASEIYYDPDPRSTVI PEDEEIIQLHFSFDQQSPWLLRLELDRAAMNDKDLTMGQV GERIKQTFKNDLFVIWSEDNDEKLIIRCRVVRPAEEDHML KKIENTMLENITLRGVENIERVVMMKYDRKVPSPTGEYVK EPEWVLETDGVNLSEVMTVPGIDPTRIYTNSFIDIMEVLG IEAGRAALYKEVYNVIASDGSYVNYRHMALLVDVMTTQGG LTSVTRHGFNRSNTGALMRCSFEETVEILFEAGASAELDD CRGVSENVILGQMAPIGTGAFDVMIDEESLVKYM Description (1)  DNA-directed RNA polymerase II /RNA/DNA Complex Functional site 1) chain A residue 483 type catalytic sequence D description 788 source MCSA : MCSA1 2) chain A residue 485 type catalytic sequence D description 788 source MCSA : MCSA1 3) chain A residue 1085 type catalytic sequence H description 788 source MCSA : MCSA1 4) chain A residue 483 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 5) chain A residue 485 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1 6) chain A residue 107 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 7) chain A residue 110 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 8) chain A residue 148 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 9) chain A residue 167 type ZN_FING sequence C description C4-type source Swiss-Prot : SWS_FT_FI1 10) chain A residue 481 type ZN_FING sequence D description C4-type source Swiss-Prot : SWS_FT_FI1

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