|
|
eF-site ID
|
5c44-I |
|
PDB Code
|
5c44 |
|
Chain
|
I |
|
click to enlarge
|
|
|
Title
|
Crystal structure of a transcribing RNA Polymerase II complex reveals a complete transcription bubble |
|
Classification
|
TRANSFERASE/DNA/RNA |
|
Compound
|
DNA-directed RNA polymerase II subunit RPB1 |
|
Source
|
ORGANISM_COMMON: Baker's yeast; ORGANISM_SCIENTIFIC: Saccharomyces cerevisiae (strain ATCC 204508 / S288c); |
|
|
Sequence
|
I: |
TTFRFCRDCNNMLYPREDKENNRLLFECRTCSYVEEAGSP
LVYRHELITNIGETAGVVQDIGSDPTLPRSDRECPKCHSR
ENVFFQSQQRRKDTSMVLFFVCLSCSHIFTSDQK
|
|
|
Description
|
(1) |
DNA-directed RNA polymerase II /RNA/DNA Complex
|
|
Functional site
|
|
|
1)
|
chain |
I |
| residue |
75-110 |
| type |
prosite |
| sequence |
CPKCHSRENVFFQSQQRRKDTSMVLFFVCLSCSHIF
|
| description |
ZF_TFIIS_1 Zinc finger TFIIS-type signature. CpkChsrenvffqSQQRRkDTSmvlffvCls...CshiF
|
| source |
prosite : PS00466
|
|
|
2)
|
chain |
I |
| residue |
6-32 |
| type |
prosite |
| sequence |
FCRDCNNMLYPREDKENNRLLFECRTC
|
| description |
RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCRDCNNMLypredkennrllfeCrtC
|
| source |
prosite : PS01030
|
|
|
3)
|
chain |
I |
| residue |
7 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU10145, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
4)
|
chain |
I |
| residue |
10 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU10145, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
5)
|
chain |
I |
| residue |
29 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU10145, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
6)
|
chain |
I |
| residue |
32 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU10145, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI3
|
|
|
7)
|
chain |
I |
| residue |
75 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00472, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
8)
|
chain |
I |
| residue |
78 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00472, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
9)
|
chain |
I |
| residue |
103 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00472, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
10)
|
chain |
I |
| residue |
106 |
| type |
BINDING |
| sequence |
C
|
| description |
BINDING => ECO:0000255|PROSITE-ProRule:PRU00472, ECO:0000269|PubMed:11313498, ECO:0000269|PubMed:11805306, ECO:0000269|PubMed:15537538, ECO:0000305|PubMed:11313499
|
| source |
Swiss-Prot : SWS_FT_FI4
|
|
|
11)
|
chain |
I |
| residue |
40 |
| type |
MOD_RES |
| sequence |
S
|
| description |
Phosphoserine => ECO:0007744|PubMed:18407956
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
|
|