eF-site ID 5c07-ABCDEFGHIJ PDB Code 5c07 Chain A, B, C, D, E, F, G, H, I, J click to enlarge Title 1E6 TCR in complex with HLA-A02 carrying YQFGPDFPIA Classification IMMUNE SYSTEM Compound HLA class I histocompatibility antigen, A-2 alpha chain Source Homo sapiens (Human) (5C07) Sequence A:  GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDA ASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLGT LRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYDG KDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAYL EGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGT FQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP B:  MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDL LKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA CRVNHVTLSQPKIVKWDRDM C:  YQFGPDFPIA D:  KEVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSR KGPELLMYTYSSGNKEDGRFTAQVDKSSKYISLFIRDSQP SDSATYLCAMRGDSSYKLIFGSGTRLLVRPDIQNPDPAVY QLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVL DMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP E:  DAGVIQSPRHEVTEMGQQVTLRCKPISGHDYLFWYRQTMM RGLELLIYFNNNVPIDDSGMPEDRFSAKMPNASFSTLKIQ PSEPRDSAVYFCASSLWEKLAKNIQYFGAGTRLSVLEDLK NVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELS WWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSA TFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAE AWGRAD F:  MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSD AASQRMEPRAPWIEQEGPEYWDGETRKVKAHSQTHRVDLG TLRGYYNQSEAGSHTVQRMYGCDVGSDWRFLRGYHQYAYD GKDYIALKEDLRSWTAADMAAQTTKHKWEAAHVAEQLRAY LEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEA TLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDG TFQKWAAVVVPSGQEQRYTCHVQHEGLPKPLTLRWEP G:  MIQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDL LKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYA CRVNHVTLSQPKIVKWDRDM H:  YQFGPDFPIA I:  KEVEQDPGPLSVPEGAIVSLNCTYSNSAFQYFMWYRQYSR KGPELLMYTYSSGNKEDGRFTAQVDKSSKYISLFIRDSQP SDSATYLCAMRGDSSYKLIFGSGTRLLVRPDIQNPDPAVY QLRDSKSSDKSVCLFTDFDSQTNVSQSKDSDVYITDKCVL DMRSMDFKSNSAVAWSNKSDFACANAFNNSIIPEDTFFP J:  DAGVIQSPRHEVTEMGQQVTLRCKPISGHDYLFWYRQTMM RGLELLIYFNNNVPIDDSGMPEDRFSAKMPNASFSTLKIQ PSEPRDSAVYFCASSLWEKLAKNIQYFGAGTRLSVLEDLK NVFPPEVAVFEPSEAEISHTQKATLVCLATGFYPDHVELS WWVNGKEVHSGVCTDPQPLKEQPALNDSRYALSSRLRVSA TFWQDPRNHFRCQVQFYGLSENDEWTQDRAKPVTQIVSAE AWGRAD Description Functional site 1) chain A residue 19 type sequence E description binding site for residue SO4 A 301 source : AC1 2) chain A residue 20 type sequence P description binding site for residue SO4 A 301 source : AC1 3) chain A residue 38 type sequence S description binding site for residue SO4 A 301 source : AC1 4) chain A residue 71 type sequence S description binding site for residue SO4 A 301 source : AC1 5) chain A residue 75 type sequence R description binding site for residue SO4 A 301 source : AC1 6) chain A residue 21 type sequence R description binding site for residue SO4 A 302 source : AC2 7) chain B residue 51 type sequence H description binding site for residue SO4 A 302 source : AC2 8) chain A residue 21 type sequence R description binding site for residue EDO B 101 source : AC3 9) chain B residue 33 type sequence S description binding site for residue EDO B 101 source : AC3 10) chain B residue 34 type sequence D description binding site for residue EDO B 101 source : AC3 11) chain D residue 92 type sequence R description binding site for residue EDO D 301 source : AC4 12) chain D residue 97 type sequence Y description binding site for residue EDO D 301 source : AC4 13) chain D residue 99 type sequence L description binding site for residue EDO D 301 source : AC4 14) chain E residue 100 type sequence L description binding site for residue EDO D 301 source : AC4 15) chain E residue 103 type sequence N description binding site for residue EDO D 301 source : AC4 16) chain D residue 60 type sequence R description binding site for residue SO4 D 302 source : AC5 17) chain C residue 8 type sequence P description binding site for residue EDO E 301 source : AC6 18) chain C residue 9 type sequence I description binding site for residue EDO E 301 source : AC6 19) chain E residue 30 type sequence D description binding site for residue EDO E 301 source : AC6 20) chain E residue 31 type sequence Y description binding site for residue EDO E 301 source : AC6 21) chain E residue 96 type sequence L description binding site for residue EDO E 301 source : AC6 22) chain E residue 97 type sequence W description binding site for residue EDO E 301 source : AC6 23) chain E residue 98 type sequence E description binding site for residue EDO E 301 source : AC6 24) chain F residue 43 type sequence Q description binding site for residue GOL F 301 source : AC7 25) chain F residue 68 type sequence K description binding site for residue GOL F 301 source : AC7 26) chain F residue 72 type sequence Q description binding site for residue GOL F 301 source : AC7 27) chain J residue 53 type sequence V description binding site for residue GOL F 301 source : AC7 28) chain F residue 13 type sequence S description binding site for residue GOL F 302 source : AC8 29) chain F residue 78 type sequence L description binding site for residue GOL F 302 source : AC8 30) chain F residue 88 type sequence S description binding site for residue GOL F 302 source : AC8 31) chain F residue 89 type sequence E description binding site for residue GOL F 302 source : AC8 32) chain F residue 91 type sequence G description binding site for residue GOL F 302 source : AC8 33) chain F residue 93 type sequence H description binding site for residue GOL F 302 source : AC8 34) chain F residue 118 type sequence Y description binding site for residue GOL F 302 source : AC8 35) chain E residue 2 type sequence A description binding site for residue GOL F 303 source : AC9 36) chain E residue 3 type sequence G description binding site for residue GOL F 303 source : AC9 37) chain E residue 27 type sequence S description binding site for residue GOL F 303 source : AC9 38) chain F residue 89 type sequence E description binding site for residue GOL F 303 source : AC9 39) chain F residue 19 type sequence E description binding site for residue EDO F 304 source : AD1 40) chain F residue 20 type sequence P description binding site for residue EDO F 304 source : AD1 41) chain F residue 71 type sequence S description binding site for residue EDO F 304 source : AD1 42) chain F residue 72 type sequence Q description binding site for residue EDO F 304 source : AD1 43) chain F residue 75 type sequence R description binding site for residue EDO F 304 source : AD1 44) chain F residue 122 type sequence D description binding site for residue SO4 F 305 source : AD2 45) chain F residue 123 type sequence Y description binding site for residue SO4 F 305 source : AD2 46) chain F residue 124 type sequence I description binding site for residue SO4 F 305 source : AD2 47) chain F residue 125 type sequence A description binding site for residue SO4 F 305 source : AD2 48) chain F residue 134 type sequence T description binding site for residue SO4 F 305 source : AD2 49) chain F residue 136 type sequence A description binding site for residue SO4 F 305 source : AD2 50) chain G residue 33 type sequence S description binding site for residue EDO G 101 source : AD3 51) chain G residue 34 type sequence D description binding site for residue EDO G 101 source : AD3 52) chain F residue 234 type sequence R description binding site for residue EDO G 102 source : AD4 53) chain F residue 242 type sequence Q description binding site for residue EDO G 102 source : AD4 54) chain G residue 10 type sequence Y description binding site for residue EDO G 102 source : AD4 55) chain G residue 11 type sequence S description binding site for residue EDO G 102 source : AD4 56) chain G residue 95 type sequence W description binding site for residue EDO G 102 source : AD4 57) chain G residue 99 type sequence M description binding site for residue EDO G 102 source : AD4 58) chain F residue 155 type sequence Q description binding site for residue GOL H 101 source : AD5 59) chain H residue 3 type sequence F description binding site for residue GOL H 101 source : AD5 60) chain H residue 4 type sequence G description binding site for residue GOL H 101 source : AD5 61) chain H residue 5 type sequence P description binding site for residue GOL H 101 source : AD5 62) chain H residue 6 type sequence D description binding site for residue GOL H 101 source : AD5 63) chain I residue 32 type sequence Y description binding site for residue GOL H 101 source : AD5 64) chain I residue 92 type sequence R description binding site for residue GOL H 101 source : AD5 65) chain I residue 97 type sequence Y description binding site for residue GOL H 101 source : AD5 66) chain J residue 97 type sequence W description binding site for residue GOL H 101 source : AD5 67) chain J residue 101 type sequence A description binding site for residue GOL H 101 source : AD5 68) chain D residue 12 type sequence S description binding site for residue GOL I 301 source : AD6 69) chain D residue 13 type sequence V description binding site for residue GOL I 301 source : AD6 70) chain I residue 66 type sequence D description binding site for residue GOL I 301 source : AD6 71) chain I residue 69 type sequence S description binding site for residue GOL I 301 source : AD6 72) chain I residue 71 type sequence Y description binding site for residue GOL I 301 source : AD6 73) chain I residue 92 type sequence R description binding site for residue EDO I 302 source : AD7 74) chain I residue 97 type sequence Y description binding site for residue EDO I 302 source : AD7 75) chain I residue 99 type sequence L description binding site for residue EDO I 302 source : AD7 76) chain J residue 103 type sequence N description binding site for residue EDO I 302 source : AD7 77) chain D residue 66 type sequence D description binding site for residue EDO I 303 source : AD8 78) chain D residue 71 type sequence Y description binding site for residue EDO I 303 source : AD8 79) chain I residue 12 type sequence S description binding site for residue EDO I 303 source : AD8 80) chain I residue 13 type sequence V description binding site for residue EDO I 303 source : AD8 81) chain D residue 18 type sequence I description binding site for residue SO4 I 304 source : AD9 82) chain D residue 77 type sequence R description binding site for residue SO4 I 304 source : AD9 83) chain I residue 18 type sequence I description binding site for residue SO4 I 304 source : AD9 84) chain I residue 77 type sequence R description binding site for residue SO4 I 304 source : AD9 85) chain H residue 7 type sequence F description binding site for residue GOL J 301 source : AE1 86) chain H residue 8 type sequence P description binding site for residue GOL J 301 source : AE1 87) chain H residue 9 type sequence I description binding site for residue GOL J 301 source : AE1 88) chain J residue 30 type sequence D description binding site for residue GOL J 301 source : AE1 89) chain J residue 31 type sequence Y description binding site for residue GOL J 301 source : AE1 90) chain J residue 96 type sequence L description binding site for residue GOL J 301 source : AE1 91) chain J residue 97 type sequence W description binding site for residue GOL J 301 source : AE1 92) chain A residue 89 type sequence E description binding site for residue GOL J 302 source : AE2 93) chain J residue 2 type sequence A description binding site for residue GOL J 302 source : AE2 94) chain J residue 3 type sequence G description binding site for residue GOL J 302 source : AE2 95) chain J residue 24 type sequence K description binding site for residue GOL J 302 source : AE2 96) chain J residue 25 type sequence P description binding site for residue GOL J 302 source : AE2 97) chain J residue 26 type sequence I description binding site for residue GOL J 302 source : AE2 98) chain J residue 27 type sequence S description binding site for residue GOL J 302 source : AE2 99) chain J residue 36 type sequence R description binding site for residue EDO J 303 source : AE3 100) chain J residue 41 type sequence R description binding site for residue EDO J 303 source : AE3 101) chain J residue 64 type sequence R description binding site for residue EDO J 303 source : AE3 102) chain J residue 85 type sequence R description binding site for residue EDO J 303 source : AE3 103) chain J residue 86 type sequence D description binding site for residue EDO J 303 source : AE3 104) chain F residue 151 type sequence H description binding site for residue SO4 J 304 source : AE4 105) chain J residue 85 type sequence R description binding site for residue SO4 J 304 source : AE4 106) chain J residue 102 type sequence K description binding site for residue SO4 J 304 source : AE4 107) chain A residue 86 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI4 108) chain F residue 86 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 source Swiss-Prot : SWS_FT_FI4 109) chain B residue 78-84 type prosite sequence YACRVNH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH source prosite : PS00290 110) chain A residue 257-263 type prosite sequence YTCHVQH description IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVNH source prosite : PS00290 111) chain D residue 189 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 112) chain G residue 58 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 113) chain G residue 91 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 114) chain G residue 94 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 115) chain I residue 189 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 116) chain B residue 48 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 117) chain B residue 58 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 118) chain B residue 91 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 119) chain B residue 94 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 120) chain G residue 19 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 121) chain G residue 41 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 122) chain G residue 48 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI3 123) chain E residue 71 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 124) chain F residue 143 type CARBOHYD sequence T description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 125) chain F residue 146 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 126) chain F residue 171 type CARBOHYD sequence Y description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 127) chain J residue 71 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 128) chain A residue 84 type CARBOHYD sequence Y description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 129) chain A residue 143 type CARBOHYD sequence T description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 130) chain A residue 146 type CARBOHYD sequence K description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 131) chain A residue 171 type CARBOHYD sequence Y description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 132) chain F residue 7 type CARBOHYD sequence Y description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 133) chain F residue 73 type CARBOHYD sequence T description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 134) chain F residue 84 type CARBOHYD sequence Y description N-linked (GlcNAc...) asparagine => ECO:0000255 source Swiss-Prot : SWS_FT_FI1 135) chain E residue 186 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI2 136) chain J residue 186 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI2 137) chain I residue 144 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI2 138) chain I residue 178 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000255|PROSITE-ProRule:PRU00498 source Swiss-Prot : SWS_FT_FI2

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