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eF-site ID
|
5bt1-ABCD |
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PDB Code
|
5bt1 |
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Chain
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A, B, C, D |
|
click to enlarge
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Title
|
histone chaperone Hif1 playing with histone H2A-H2B dimer |
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Classification
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CHAPERONE |
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Compound
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HAT1-interacting factor 1 |
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Source
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Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (H2B1_YEAST) |
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Sequence
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A: |
RHKVQIDMERQVQIAKDLLAQKKFLEAAKRCQQTLDSLPK
DGLLPDPELFTIFAQAVYNMEVQNSHELANFSPANEHDDE
IEDVSQLRKSGFHIYFENDLYENALDLLAQALMLLGRPTA
DGQSLTENSRLRIGDVYILMGDIEREAEMFSRAIHHYLKA
LGYYKTLKPAEQVTEKVIQAEFLVCDALRWVDQVPAKDKL
KRFKHAKALLEKHMTTRPKDSELQQARLAQIQDDIDEVQE
NQQH
|
| B: |
KVQIDMERQVQIAKDLLAQKKFLEAAKRCQQTLDSLPKDG
LLPDPELFTIFAQAVYNMEVQNSGNLFRLALHELANFSPA
NEHDDEIEDVSQLRKSGFHIYFENDLYENALDLLAQALML
LGRPTADGQSLTENSRLRIGDVYILMGDIEREAEMFSRAI
HHYLKALGYYKTLKPAEQVTEKVIQAEFLVCDALRWVDQV
PAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQDD
IDEVQENQQ
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| C: |
QSRSAKAGLTFPVGRVHRLLRRGNYAQRIGSGAPVYLTAV
LEYLAAEILELAGNAARDNKKTRIIPRHLQLAIRNDDELN
KLLGN
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| D: |
KETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERI
ATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSE
GTRAVTKYSS
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Description
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Functional site
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|
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1)
|
chain |
C |
| residue |
22-28 |
| type |
prosite |
| sequence |
AGLTFPV
|
| description |
HISTONE_H2A Histone H2A signature. AGLtFPV
|
| source |
prosite : PS00046
|
|
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2)
|
chain |
D |
| residue |
95-117 |
| type |
prosite |
| sequence |
REIQTAVRLILPGELAKHAVSEG
|
| description |
HISTONE_H2B Histone H2B signature. REIQTavRlILpGELaKHAVSEG
|
| source |
prosite : PS00357
|
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3)
|
chain |
D |
| residue |
123 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:10642555, ECO:0000269|PubMed:12535538, ECO:0000269|PubMed:12535539, ECO:0000269|PubMed:14660635, ECO:0000269|PubMed:15280549, ECO:0000269|PubMed:16432255
|
| source |
Swiss-Prot : SWS_FT_FI11
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|
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4)
|
chain |
C |
| residue |
21 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-acetyllysine; alternate => ECO:0000269|PubMed:19113941
|
| source |
Swiss-Prot : SWS_FT_FI5
|
|
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5)
|
chain |
D |
| residue |
46 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6-succinyllysine => ECO:0000269|PubMed:22389435
|
| source |
Swiss-Prot : SWS_FT_FI8
|
|
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6)
|
chain |
D |
| residue |
37 |
| type |
MOD_RES |
| sequence |
K
|
| description |
N6,N6-dimethyllysine => ECO:0000269|PubMed:19113941
|
| source |
Swiss-Prot : SWS_FT_FI9
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