eF-site ID 5bpk-D PDB Code 5bpk Chain D click to enlarge Title Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases Classification HYDROLASE Compound Gamma-glutamyltranspeptidase (Ggt) Source Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (O25743_HELPY) Sequence D:  TTHYSVADRWGNAVSVTYTINASYGSAASIDGAGFLLNNE MDDFSIKPGNPNLYGLVGGDANAIEANKRPLSSMSPTIVL KNNKVFLVVGSPGGSRIITTVLQVISNVIDYNMNISEAVS APRFHMQWLPDELRIEKFGMPADVKDNLTKMGYQIVTKPV MGDVNAIQVLPKTKGSVFYGSTDPRKEF Description Functional site 1) chain D residue 499 type sequence S description binding site for residue EDO A 404 source : AC4 2) chain D residue 526 type sequence N description binding site for residue EDO C 710 source : AE2 3) chain D residue 389 type sequence W description binding site for residue EDO B 402 source : AE5 4) chain D residue 389 type sequence W description binding site for residue EDO B 403 source : AE6 5) chain D residue 391 type sequence N description binding site for residue EDO B 403 source : AE6 6) chain D residue 565 type sequence K description binding site for residue EDO B 405 source : AE7 7) chain D residue 388 type sequence R description binding site for residue EDO B 412 source : AF5 8) chain D residue 499 type sequence S description binding site for residue EDO D 702 source : AF7 9) chain D residue 510 type sequence D description binding site for residue EDO D 703 source : AF8 10) chain D residue 511 type sequence E description binding site for residue EDO D 703 source : AF8 11) chain D residue 533 type sequence Q description binding site for residue EDO D 703 source : AF8 12) chain D residue 521 type sequence A description binding site for residue EDO D 704 source : AF9 13) chain D residue 525 type sequence D description binding site for residue EDO D 704 source : AF9 14) chain D residue 501 type sequence P description binding site for residue EDO D 705 source : AG1 15) chain D residue 502 type sequence R description binding site for residue EDO D 705 source : AG1 16) chain D residue 503 type sequence F description binding site for residue EDO D 705 source : AG1 17) chain D residue 514 type sequence I description binding site for residue EDO D 705 source : AG1 18) chain D residue 515 type sequence E description binding site for residue EDO D 705 source : AG1 19) chain D residue 518 type sequence G description binding site for residue EDO D 705 source : AG1 20) chain D residue 495 type sequence S description binding site for residue EDO D 706 source : AG2 21) chain D residue 560 type sequence S description binding site for residue EDO D 706 source : AG2 22) chain D residue 561 type sequence T description binding site for residue EDO D 706 source : AG2 23) chain D residue 485 type sequence S description binding site for residue EDO D 707 source : AG3 24) chain D residue 490 type sequence Y description binding site for residue EDO D 707 source : AG3 25) chain D residue 422 type sequence D description binding site for residue EDO D 708 source : AG4 26) chain D residue 423 type sequence F description binding site for residue EDO D 708 source : AG4 27) chain D residue 429 type sequence N description binding site for residue EDO D 708 source : AG4 28) chain D residue 431 type sequence N description binding site for residue EDO D 708 source : AG4 29) chain D residue 435 type sequence L description binding site for residue EDO D 708 source : AG4 30) chain D residue 441 type sequence N description binding site for residue EDO D 708 source : AG4 31) chain D residue 387 type sequence D description binding site for residue EDO D 709 source : AG5 32) chain D residue 388 type sequence R description binding site for residue EDO D 709 source : AG5 33) chain D residue 389 type sequence W description binding site for residue EDO D 709 source : AG5 34) chain D residue 390 type sequence G description binding site for residue EDO D 709 source : AG5 35) chain D residue 555 type sequence S description binding site for residue EDO D 709 source : AG5 36) chain D residue 557 type sequence F description binding site for residue EDO D 709 source : AG5 37) chain D residue 522 type sequence D description binding site for residue EDO D 710 source : AG6 38) chain D residue 525 type sequence D description binding site for residue EDO D 710 source : AG6 39) chain D residue 475 type sequence R description binding site for residue EDO D 711 source : AG7 40) chain D residue 513 type sequence R description binding site for residue EDO D 711 source : AG7 41) chain D residue 381 type sequence T description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 42) chain D residue 397 type sequence Y description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 43) chain D residue 398 type sequence T description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 44) chain D residue 400 type sequence N description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 45) chain D residue 419 type sequence E description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 46) chain D residue 422 type sequence D description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 47) chain D residue 433 type sequence Y description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 48) chain D residue 451 type sequence S description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 49) chain D residue 452 type sequence S description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 50) chain D residue 453 type sequence M description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 51) chain D residue 471 type sequence P description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 52) chain D residue 472 type sequence G description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 53) chain D residue 473 type sequence G description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 54) chain D residue 476 type sequence I description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG8 55) chain D residue 381 type sequence T description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 56) chain D residue 397 type sequence Y description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 57) chain D residue 398 type sequence T description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 58) chain D residue 400 type sequence N description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 59) chain D residue 419 type sequence E description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 60) chain D residue 422 type sequence D description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 61) chain D residue 433 type sequence Y description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 62) chain D residue 451 type sequence S description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 63) chain D residue 452 type sequence S description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 64) chain D residue 453 type sequence M description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 65) chain D residue 471 type sequence P description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 66) chain D residue 472 type sequence G description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 67) chain D residue 473 type sequence G description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9 68) chain D residue 476 type sequence I description binding site for Di-peptide 4UD D 701 and THR D 380 source : AG9

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