eF-site ID 5bpk-C PDB Code 5bpk Chain C click to enlarge Title Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases Classification HYDROLASE Compound Gamma-glutamyltranspeptidase (Ggt) Source Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (O25743_HELPY) Sequence C:  TTHYSVADRWGNAVSVTYTINASYGSAASIDGAGFLLNNE MDDFSIKPGNPNLYGLVGGDANAIEANKRPLSSMSPTIVL KNNKVFLVVGSPGGSRIITTVLQVISNVIDYNMNISEAVS APRFHMQWLPDELRIEKFGMPADVKDNLTKMGYQIVTKPV MGDVNAIQVLPKTKGSVFYGSTDPRKEF Description Functional site 1) chain C residue 565 type sequence K description binding site for residue EDO A 402 source : AC2 2) chain C residue 499 type sequence S description binding site for residue EDO A 404 source : AC4 3) chain C residue 460 type sequence K description binding site for residue EDO A 406 source : AC6 4) chain C residue 461 type sequence N description binding site for residue EDO A 406 source : AC6 5) chain C residue 380 type sequence T description binding site for residue 4UD C 701 source : AD2 6) chain C residue 398 type sequence T description binding site for residue 4UD C 701 source : AD2 7) chain C residue 400 type sequence N description binding site for residue 4UD C 701 source : AD2 8) chain C residue 419 type sequence E description binding site for residue 4UD C 701 source : AD2 9) chain C residue 422 type sequence D description binding site for residue 4UD C 701 source : AD2 10) chain C residue 433 type sequence Y description binding site for residue 4UD C 701 source : AD2 11) chain C residue 451 type sequence S description binding site for residue 4UD C 701 source : AD2 12) chain C residue 452 type sequence S description binding site for residue 4UD C 701 source : AD2 13) chain C residue 453 type sequence M description binding site for residue 4UD C 701 source : AD2 14) chain C residue 472 type sequence G description binding site for residue 4UD C 701 source : AD2 15) chain C residue 473 type sequence G description binding site for residue 4UD C 701 source : AD2 16) chain C residue 476 type sequence I description binding site for residue 4UD C 701 source : AD2 17) chain C residue 390 type sequence G description binding site for residue EDO C 702 source : AD3 18) chain C residue 462 type sequence N description binding site for residue EDO C 702 source : AD3 19) chain C residue 463 type sequence K description binding site for residue EDO C 702 source : AD3 20) chain C residue 464 type sequence V description binding site for residue EDO C 702 source : AD3 21) chain C residue 422 type sequence D description binding site for residue EDO C 703 source : AD4 22) chain C residue 423 type sequence F description binding site for residue EDO C 703 source : AD4 23) chain C residue 424 type sequence S description binding site for residue EDO C 703 source : AD4 24) chain C residue 429 type sequence N description binding site for residue EDO C 703 source : AD4 25) chain C residue 431 type sequence N description binding site for residue EDO C 703 source : AD4 26) chain C residue 435 type sequence L description binding site for residue EDO C 703 source : AD4 27) chain C residue 441 type sequence N description binding site for residue EDO C 703 source : AD4 28) chain C residue 501 type sequence P description binding site for residue EDO C 704 source : AD5 29) chain C residue 502 type sequence R description binding site for residue EDO C 704 source : AD5 30) chain C residue 503 type sequence F description binding site for residue EDO C 704 source : AD5 31) chain C residue 514 type sequence I description binding site for residue EDO C 704 source : AD5 32) chain C residue 515 type sequence E description binding site for residue EDO C 704 source : AD5 33) chain C residue 518 type sequence G description binding site for residue EDO C 704 source : AD5 34) chain C residue 495 type sequence S description binding site for residue EDO C 705 source : AD6 35) chain C residue 560 type sequence S description binding site for residue EDO C 705 source : AD6 36) chain C residue 561 type sequence T description binding site for residue EDO C 705 source : AD6 37) chain C residue 391 type sequence N description binding site for residue EDO C 706 source : AD7 38) chain C residue 387 type sequence D description binding site for residue EDO C 707 source : AD8 39) chain C residue 390 type sequence G description binding site for residue EDO C 707 source : AD8 40) chain C residue 555 type sequence S description binding site for residue EDO C 707 source : AD8 41) chain C residue 485 type sequence S description binding site for residue EDO C 708 source : AD9 42) chain C residue 490 type sequence Y description binding site for residue EDO C 708 source : AD9 43) chain C residue 516 type sequence K description binding site for residue EDO C 709 source : AE1 44) chain C residue 538 type sequence P description binding site for residue EDO C 709 source : AE1 45) chain C residue 539 type sequence V description binding site for residue EDO C 709 source : AE1 46) chain C residue 522 type sequence D description binding site for residue EDO C 710 source : AE2 47) chain C residue 525 type sequence D description binding site for residue EDO C 710 source : AE2 48) chain C residue 526 type sequence N description binding site for residue EDO C 710 source : AE2 49) chain C residue 389 type sequence W description binding site for residue EDO C 711 source : AE3 50) chain C residue 444 type sequence E description binding site for residue EDO B 409 source : AF2 51) chain C residue 499 type sequence S description binding site for residue EDO D 702 source : AF7 52) chain C residue 526 type sequence N description binding site for residue EDO D 710 source : AG6 53) chain C residue 380-404 type prosite sequence TTHYSVADRWGNAVSVTYTINASYG description G_GLU_TRANSPEPTIDASE Gamma-glutamyltranspeptidase signature. TTHySVadrwGNaVSvTyTINasYG source prosite : PS00462

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