eF-site ID 5bpk-A PDB Code 5bpk Chain A click to enlarge Title Varying binding modes of inhibitors and structural differences in the binding pockets of different gamma-glutamyltranspeptidases Classification HYDROLASE Compound Gamma-glutamyltranspeptidase (Ggt) Source Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (O25743_HELPY) Sequence A:  ASYPPIKNTKVGLALSSHPLASEIGQKVLEEGGNAIDAAV AIGFALAVVHPAAGNIGGGGFAVIHLANGENVALDFREKA PLKATKNMFLDKQGNVVPKLSEDGYLAAGVPGTVAGMEAM LKKYGTKKLSQLIDPAIKLAENGYAISQRQAETLKEARER FLKYSSSKKYFFKKGHLDYQEGDLFVQKDLAKTLNQIKTL GAKGFYQGQVAELIEKDMKKNGGIITKEDLASYNVKWRKP VVGSYRGYKIISMSPPSSGGTHLIQILNVMENADLSALGY GASKNIHIAAEAMRQAYADRSVYMGDADFVSVPVDKLINK AYAKKIFDTIQPDTVTPSSQIKPGMGQL Description Functional site 1) chain A residue 29 type sequence Y description binding site for residue EDO A 401 source : AC1 2) chain A residue 76 type sequence H description binding site for residue EDO A 402 source : AC2 3) chain A residue 180 type sequence L description binding site for residue EDO A 403 source : AC3 4) chain A residue 184 type sequence R description binding site for residue EDO A 403 source : AC3 5) chain A residue 197 type sequence F description binding site for residue EDO A 403 source : AC3 6) chain A residue 198 type sequence F description binding site for residue EDO A 403 source : AC3 7) chain A residue 204 type sequence D description binding site for residue EDO A 403 source : AC3 8) chain A residue 205 type sequence Y description binding site for residue EDO A 403 source : AC3 9) chain A residue 28 type sequence S description binding site for residue EDO A 404 source : AC4 10) chain A residue 29 type sequence Y description binding site for residue EDO A 404 source : AC4 11) chain A residue 341 type sequence D description binding site for residue EDO A 405 source : AC5 12) chain A residue 345 type sequence N description binding site for residue EDO A 405 source : AC5 13) chain A residue 272 type sequence R description binding site for residue EDO A 406 source : AC6 14) chain A residue 273 type sequence G description binding site for residue EDO A 406 source : AC6 15) chain A residue 274 type sequence Y description binding site for residue EDO A 406 source : AC6 16) chain A residue 297 type sequence E description binding site for residue EDO A 407 source : AC7 17) chain A residue 94 type sequence N description binding site for residue EDO A 408 source : AC8 18) chain A residue 188 type sequence L description binding site for residue EDO A 408 source : AC8 19) chain A residue 189 type sequence K description binding site for residue EDO A 408 source : AC8 20) chain A residue 191 type sequence S description binding site for residue EDO A 408 source : AC8 21) chain A residue 194 type sequence K description binding site for residue EDO A 408 source : AC8 22) chain A residue 145 type sequence A description binding site for residue EDO A 409 source : AC9 23) chain A residue 148 type sequence K description binding site for residue EDO A 409 source : AC9 24) chain A residue 149 type sequence K description binding site for residue EDO A 409 source : AC9 25) chain A residue 263 type sequence W description binding site for residue EDO A 409 source : AC9 26) chain A residue 260 type sequence N description binding site for residue EDO A 410 source : AD1 27) chain A residue 103 type sequence R description binding site for residue 4UD C 701 source : AD2 28) chain A residue 91 type sequence H description binding site for residue EDO C 702 source : AD3 29) chain A residue 93 type sequence A description binding site for residue EDO C 702 source : AD3 30) chain A residue 326 type sequence R description binding site for residue EDO C 703 source : AD4 31) chain A residue 30 type sequence P description binding site for residue EDO C 705 source : AD6 32) chain A residue 93 type sequence A description binding site for residue EDO C 706 source : AD7 33) chain A residue 194 type sequence K description binding site for residue EDO C 706 source : AD7 34) chain A residue 202 type sequence H description binding site for residue EDO C 706 source : AD7 35) chain A residue 296 type sequence M description binding site for residue EDO C 708 source : AD9 36) chain A residue 311 type sequence N description binding site for residue EDO C 708 source : AD9 37) chain A residue 152 type sequence T description binding site for residue EDO C 711 source : AE3 38) chain A residue 201 type sequence G description binding site for residue EDO C 711 source : AE3 39) chain A residue 202 type sequence H description binding site for residue EDO C 711 source : AE3 40) chain A residue 27 type sequence A description binding site for residue EDO D 702 source : AF7 41) chain A residue 304 type sequence L description binding site for residue EDO D 704 source : AF9 42) chain A residue 29 type sequence Y description binding site for residue EDO D 706 source : AG2 43) chain A residue 82-109 type prosite sequence IGGGGFAVIHLANGENVALDFREKAPLK description PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGGGGFAVIHlAngenvaldfrek......APLK source prosite : PS00107

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