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Title
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Kinetics by X-ray crystallography: Tl+-substitution of bound K+ in the E2.MgF42-.2K+ crystal after 0.75 min. |
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Classification
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HYDROLASE/TRANSPORT PROTEIN |
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Compound
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Na, K-ATPase alpha subunit |
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Source
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ORGANISM_COMMON: Spiny dogfish; ORGANISM_SCIENTIFIC: Squalus acanthias; |
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Sequence
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A: |
LDELKKEVSMDDHKLSLDELHNKYGTDLTRGLTNARAKEI
LARDGPNSLTPPPTTPEWIKFCRQLFGGFSILLWIGAILC
FLAYGIQAATEDEPANDNLYLGVVLSTVVIVTGCFSYYQE
AKSSRIMDSFKNMVPQQALVIRDGEKSTINAEFVVAGDLV
EVKGGDRIPADLRIISAHGCKVDNSSLTGESEPQTRSPEF
SSENPLETRNIAFFSTNCVEGTARGVVVYTGDRTVMGRIA
TLASGLEVGRTPIAIEIEHFIHIITGVAVFLGVSFFILSL
ILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRM
ARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM
WFDNQIHEADTTENQSGAAFDKTSATWSALSRIAALCNRA
VFQAGQDNVPILKRSVAGDASESALLKCIELCCGSVQGMR
DRNPKIVEIPFNSTNKYQLSIHENEKSSESRYLLVMKGAP
ERILDRCSTILLNGAEEPLKEDMKEAFQNAYLELGGLGER
VLGFCHFALPEDKYNEGYPFDADEPNFPTTDLCFVGLMAM
IDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV
GIISEGNETIEDIAARLNIPIGQVNPRDAKACVVHGSDLK
DLSTEVLDDILHYHTEIVFARTSPQQKLIIVEGCQRQGAI
VAVTGDGVNDSPALKKADIGVAMGISGSDVSKQAADMILL
DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL
VFIIGNVPLPLGTVTILCIDLGTDMVPAISLAYEQAESDI
MKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFSYFV
ILAENGFLPMDLIGKRVRWDDRWISDVEDSFGQQWTYEQR
KIVEFTCHTSFFISIVVVQWADLIICKTRRNSIFQQGMKN
KILIFGLFEETALAAFLSYCPGTDVALRMYPLKPSWWFCA
FPYSLIIFLYDEMRRFIIRRSPGGWVEQETYY
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| B: |
FLGRTGSSWFKIFLFYLIFYGCLAGIFIGTIQVLLLTLSD
FEPKYQDRVAPPGLSHAPYAIKTEISFSISNPKSYESFVK
SMHKLMDLYNESSQAGNSPFEDCSDTPADYIKRGDLDDSQ
GQKKACRFSRMWLKNCGYAEGKPCVVAKLNRIIGFYPKPL
KNTTDLPEELQANYNQYVLPLRCAAREKIGSIEYFGLGGY
AGFPLQYYPYYGKRLQKKYLQPLLAIQFTNLTQNMELRIE
CKVYGENIDYSEKDRFRGRFEVKIEVKS
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| G: |
EGPDNDERFTYDYYRLRVVGLIVAAVLCVIGIIILLAGK
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Description
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