eF-site ID 5anb-ABCDEFGHIJKN PDB Code 5anb Chain A, B, C, D, E, F, G, H, I, J, K, N click to enlarge Title Mechanism of eIF6 release from the nascent 60S ribosomal subunit Classification TRANSLATION Compound 60S RIBOSOMAL PROTEIN L3 Source ORGANISM_COMMON: SLIME MOLD; ORGANISM_SCIENTIFIC: DICTYOSTELIUM DISCOIDEUM; Sequence A:  MSHRKFEAPRHGNLGFRPRKRAARHQGKVKSFPKDDRTQK VHLTAFMGYKAGMTHVVRDLEKPGSKMHKKEIVEAVTIIE CPPMYIVGLVGYVETAQGLKTYKTVWAQHLSDNFRRRLYK NWYKSKSKKAFTKYVKQYETEEGKKSIEASLQAIKKRCSV VRVIAHTQVHKLKLTQKKAHVLEIQVNGGSIVEKVNFAVA NFEKTVNVTGVFAENELIDVIGVTKGKGFNGVIKRWGVRK LPRKTHKGLRKVACIGAWHPSRVSTTVPRAGQLGYHHRVE RNKKIYRIGQAQPEDGKQISTGKTEFDLTEKTINPMGGFA HYGMVKHEFLMLKGCVAGPRKRALTLRKSITTQTGRAALE KITLKFIDTSSKFGHGLHQTAEDKTKYFGVKKSRSTKA B:  MKVINSSRKVQIPENVTVDVKGRSVKVTGPRGTLSKSFDH ASVDINLVGKKELTVDLWFGNRKQIACIKTITSIIENMIT GVTKGYEYKMRFVYAHFPINVAVTDGGRVVEIRNFFGEKI VRRIELLDGITCYRNEKAKDEIVLTGNSLELLSQSCATIQ LRSAIKYKDVRKFLDGIYVSERNVLESN C:  MSGAGSKRKNVFIEKATKLFTTYDKMIVAEADFVGSSQLQ KIRKSIRGIGAVLMGKKTMIRKVIRDLADSKPELDALNTY LKQNTCIIFCKDNIAEVKRVINTQRVGAPAKAGVFAPNDV IIPAGPTGMEPTQTSFLQDLKIATKINRGQIDIVNEVHII KTGQKVGASEATLLQKLNIKPFTYGLEPKIIYDAGACYSP SISEE D:  MPPKVDPSEKVEVFLRVCGGEAGAMSTLAPKLGPLGVSPK KVGDDIAKATQPWKGMKVSVKLTIQNRIAVPEVLPSASAL VIKALKEPPRDRKKEKNIKHNGNIPLEEICKIAKTMRFKS LAVDFKGSVLEILGTAHSVGCKVNGKSPRDIQAGIQSGEI EVVEPK E:  MSKAQAVGSNYRVSLGLPVGAVMNSADNSGAKNLYVIAVK GIKGRLNRLPSAGVGDMVMATVKKGKPELRKKVCTGLVVR QRKHWKRKDGVYIYFEDNAGVMCNPKGEVKGNILGPVAKE CSDLWPKVATNAGTIV F:  MGRRPARCYRYCKNKPYIKSRYCRGVPDAKIRIFDLGRKK ASTDEFPLCVHLISLEKEQLSSEAIEAGRISCNKYISKTG GKDSFHMRVRVHPWHVLRINKMLSCAGADRLQTGMRGAFG KPMGTVARVNIGQIIFSIRTRDNMLANVVEALRRSSYKFP GRQKIVVSKKWGFTAYNREAYQKLKADGRLMNDGANVKVI TNHGTLAQYAKDIAAAN G:  MKTSLCNYSEFKIYPARGMKFVRGDSKVFHFINTKVESLF FRKINPRDIRWSMVYRRIYKNTTTDVSAK H:  IEPSLVILARKYKCDKMICRKCYARLHPRAVNCRKKKCGH SNNLRPKKKLLK I:  MATRLQYENSCDVGVFLKLTNKYCLVGQCGSKQFLHTVEN RLADHIPVVETSIAGTRIVGRLSAGNKNGLLLPNTCTDQE LQQIRNSLPDDVVVQRIEEKFSALGNCIATNDYVALVHPD IDRETEEIIADVLGVEVFRQTVSGNVLVGTYCALTNQGAL VHPMTSIADQDELSSLLQVPLVAGTVNRGNECVAAGCVVN DWTAIVGADTTATEISVIESIFAL J:  MSIFTPTNQIRLTNVAVVRMKRAGKRFEIACYKNKVVGWR SGVEKDLDEVLQTHSVFVNVSKGQVAKKEDLISAFGTDDQ TEICKQILTKGEVQVSDKERHTQLEQMFRDIATIVADKCV NPETKRPYTVILIERAMKDIHYSVKTNKSTKQQALEVIKQ LKEKMKIERAHMRLRFILPVNEGKKLKEKLKPLIKVIESE DYGQQLEIVCLIDPGCFREIDELIKKETKGKGSLEVLNLK DVEEGDEKFE K:  MVLNSLDKMIQLQKNTANIRNICVLAHVDHGKTTLADCLI SSNGIISSRLAGKLRYMDSREDEQIRGITMKSSAISLHYA TGNEEYLINLIDSPGHVDFSSEVSTAVRICDGCIIVVDAV EGVCPQTQAVLRQAWLENIRPVLVINKIDRLIVELKFTPQ EAYSHLKNILEQINALTGTLFTSKVLEERAERETESQVNP NSEQGEQVYDWSTGLEDTDDSHLYFSPEQGNVVFTSAIDG WGFGIEHFARIYSQKIGIKKEVLMKTLWGDYYINMKAKKI MKGDQAKGKKPLFVQLILENIWSLYDAVLKKDKDKIDKIV TSLGLKIGAREARHSDPKVQINAICSQWLPISHAVLAMVC QKLPSPLDITAERVERLMCTGSQTFDSFPPETQALKAAFM KCGSEDTAPVIIFVSKMFAVDAKALPQNKPRPLTQEEIAQ RRERARQRHAEKLAAAQGQAPLEPTQDGSAIETCPKGEEP RGDEQQVESMTPKPVLQEENNQESFIAFARVFSGVARRGK KIFVLGPKYSPLEFLRRVPLGFSAPPDGLPQVPHMAYCAL ENLYLLMGRELEYLEEVPPGNVLGIGGLQDFVLKSATLCS LPSCPPFIPLNFEATPIVRVAVEPKHPSEMPQLVKGMKLL NQADPCVQILIQETGEHVLVTAGEVHLQRCLDDLKERFAK IHISVSEPIIPFRETITKPPKVDMVNEEIGKQQKVAVIHQ MKEDQSKIPEGIQVDSDGLITITTPNKLATLSVRAMPLPE EVTQILEENSDLIRSMEQLTSSLNEGENTHMIHQKTQEKI WEFKGKLEQHLTGRRWRNIVDQIWSFGPRKCGPNILVNKS EDFQNSVWTGPADKASKEASRYRDLGNSIVSGFQLATLSG PMCEEPLMGVCFVLEKWDLSKFEEQGASDLAKEGQEENET CSGGNENQELQDGCSEAFEKRTSQKGESPLTDCYGPFSGQ LIATMKEACRYALQVKPQRLMAAMYTCDIMATGDVLGRVY AVLSKREGRVLQEEMKEGTDMFIIKAVLPVAESFGFADEI RKRTSGLASPQLVFSHWEIIPSDPFWVPTTEEEYLHFGEK ADSENQARKYMNAVRKRKGLYVEEKIVEHAEKQRTLSKNK N:  AUUAGCAGUUUCGGGGGCGUAAUGCUCUCAGCUGAUUCUC AAACUCUGAACAUUUUUGGUAAGCAGAACUGGCGAUGUGG GUUGAACCAAAUAUUGGGAUAAGACGUCUAACAUUCACUA AUAGAUACCACAAAAGGUGUUAGUUCAUUAAGACAGCAGG ACGGUGGCCAUGGAAGUCGGUAUCCGCUAAGGAGUGUGUA ACAACUCACCUGCCAAAUGGACUAGCCCUGAAAAUGGAUG ACGCUAGCAGUGGAUGGUCGAUGCCCAAUCGUUAAAAGAA GUGAUAAUACUUUUAACAAUCCAACUGUUUAAUUAAAACA AAGCAUUGCGAUAAGCUUAAAAGCUUUUGACGCAAUGUGA UUUCUGCCCAGUGCUCUGAAUGUCAAAGUGAAGAGAUUCA ACCUAGCACGGGUAAACGGCGGGAGUAACUAUGACUCUCU UAAGGUAGCCAAAUGCCUCGUCAUCUAAUUAGUGACGCGC AUGAAUGGAUCAAUGAGAUUCCCACUGUCCCUAACUACUA UACAGCGAAACCACUGCAAGGGGAACGGGCCUUGCAAAAA CAGCGGGGAAAGAAGACCCUGUUGAGCUUGACUCUAGUCU GAUAUUAACAGUUUCAGGUGGGGAGUUUGGCUGGGGCGGC ACAUUUGUUAAAAGAUAACGCAAGUGUCCAAAGGCAGGCU CAGUGAGAACAGAAAUCUCACGUAGAGUAAAAGGGCAAAA GCCUGCUUGAUUCUGAUUUUCAGUACUAAUCGGAACUGGG AAACCAGGGCCUAUCGAUCCUUUAUGUGCUUAAAUCUUAA CCCUAGAGGUGUCAGAAAAGUUACCACAGGGAUAACUGGC UUGUGGCAGCCAAGCGCUCAUAGCGACGCUGCUUUUUGAU CCUUCGAUGUCGGCUCUUCUUAUCAUUGUGAAGCAGAAUU CACAAAGUGUUGGAUUGUUCACCCACUAACAAGGAACGUG AGCUGGGUUUAGACCGUCGUGAGACAGGUUAGUUUUACCC UACUGUUGUCAAUUGUUUGCGUAAUAGUAGCAUGAUUUAG UACGAGAGGAACUGUCAUGCCGGAUCACUGGUCUGUAGGU UUAUUUGACAAAAUAGUGACCUGCCGCUACCAUCCGUUGG AUAAUGGCUGAACGCCUCUAAGUCAGAAUCCAUUCUAGAA AC Description (1)  60S RIBOSOMAL PROTEIN L3, 60S RIBOSOMAL PROTEIN L9, 60S ACIDIC RIBOSOMAL PROTEIN P0, 60S RIBOSOMAL PROTEIN L12, 60S RIBOSOMAL PROTEIN L23, 60S RIBOSOMAL PROTEIN L10, 60S RIBOSOMAL PROTEIN L24, UBIQUITIN-60S RIBOSOMAL PROTEIN L40, EUKARYOTIC TRANSLATION INITIATION FACTOR 6, RIBOSOME MATURATION PROTEIN SBDS, ELONGATION FACTOR TU GTP-BINDING DOMAIN-CONTAINING PROTEIN 1 Functional site 1) chain B residue 161-182 type prosite sequence LRSAIKYKDVRKFLDGIYVSER description RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. LrsaIkyKdvRkFlDGIYVseR source prosite : PS00700 2) chain K residue 92 type BINDING sequence D description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 3) chain K residue 146 type BINDING sequence N description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 4) chain K residue 26 type BINDING sequence A description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 5) chain K residue 528 type MOD_RES sequence K description N6-acetyllysine => ECO:0007744|PubMed:19608861 source Swiss-Prot : SWS_FT_FI2 6) chain F residue 108-129 type prosite sequence ADRLQTGMRGAFGKPMGTVARV description RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPmGtvARV source prosite : PS01257 7) chain G residue 8-25 type prosite sequence YSEFKIYPARGMKFVRGD description RIBOSOMAL_L24E Ribosomal protein L24e signature. YsEfkIyPArGmkFvRgD source prosite : PS01073 8) chain A residue 212-235 type prosite sequence FAENELIDVIGVTKGKGFNGVIKR description RIBOSOMAL_L3 Ribosomal protein L3 signature. FaeneliDviGvTkGKGfnGvikR source prosite : PS00474 9) chain J residue 44-63 type prosite sequence EKDLDEVLQTHSVFVNVSKG description UPF0023 Uncharacterized protein family UPF0023 signature. EkdLDEVLqthsVFvnvsKG source prosite : PS01267

Display surface Download Links