eF-site ID 5ame-B PDB Code 5ame Chain B click to enlarge Title Crystal structure of the bromodomain of human surface epitope engineered BRD1A in complex with 3D Consortium fragment 4-acetyl- piperazin-2-one (SGC - Diamond I04-1 fragment screening) Classification TRANSCRIPTION Compound BROMODOMAIN-CONTAINING PROTEIN 1 Source (BRD1_HUMAN) Sequence B:  SMEQVAMELRLTELTRLLRSVLDQLQDKDPARIFAQPVSL KEVPDYLDHIKHPMDFATMRKRLEAQGYKNLHEFEEDFDL IIDNCMKYNARDTVFYRAAVRLRDQGGVVLRQARREVDSI GLE Description (1)  BROMODOMAIN-CONTAINING PROTEIN 1 Functional site 1) chain B residue 110 type sequence N description BINDING SITE FOR RESIDUE PW3 B 1145 source : AC1 2) chain B residue 116 type sequence F description BINDING SITE FOR RESIDUE PW3 B 1145 source : AC1 3) chain B residue 107 type sequence M description BINDING SITE FOR RESIDUE NA B 1146 source : AC2 4) chain B residue 110 type sequence N description BINDING SITE FOR RESIDUE NA B 1146 source : AC2 5) chain B residue 117 type sequence Y description BINDING SITE FOR RESIDUE NA B 1146 source : AC2 6) chain B residue 62 type CROSSLNK sequence K description Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 source Swiss-Prot : SWS_FT_FI1

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