eF-site ID 5akt-B PDB Code 5akt Chain B click to enlarge Title Transthyretin binding heterogeneity and anti-amyloidogenic activity of natural polyphenols and their metabolites: resveratrol-4'-O- glucuronide Classification TRANSPORT PROTEIN Compound TRANSTHYRETIN Source (TTHY_HUMAN) Sequence B:  CPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKT SESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHE HAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTN Description Functional site 1) chain B residue 72 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1126 source : AC1 2) chain B residue 90 type sequence H description BINDING SITE FOR RESIDUE SO4 A 1126 source : AC1 3) chain B residue 35 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1127 source : AC2 4) chain B residue 41 type sequence W description BINDING SITE FOR RESIDUE SO4 A 1127 source : AC2 5) chain B residue 15 type sequence K description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 6) chain B residue 15 type sequence K description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 7) chain B residue 17 type sequence L description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 8) chain B residue 54 type sequence E description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 9) chain B residue 110 type sequence L description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 10) chain B residue 110 type sequence L description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 11) chain B residue 117 type sequence S description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 12) chain B residue 117 type sequence S description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 13) chain B residue 118 type sequence T description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 14) chain B residue 119 type sequence T description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 15) chain B residue 119 type sequence T description BINDING SITE FOR RESIDUE R4G B 1128 source : AC3 16) chain B residue 98 type CARBOHYD sequence N description N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:16335952, ECO:0000269|PubMed:19167329 source Swiss-Prot : SWS_FT_FI5 17) chain B residue 10 type MOD_RES sequence C description Sulfocysteine => ECO:0000269|PubMed:17175208, ECO:0007744|PDB:2H4E source Swiss-Prot : SWS_FT_FI2 18) chain B residue 42 type MOD_RES sequence E description 4-carboxyglutamate; in a patient with Moyamoya disease => ECO:0000269|PubMed:18221012 source Swiss-Prot : SWS_FT_FI3 19) chain B residue 52 type MOD_RES sequence S description Phosphoserine => ECO:0000250|UniProtKB:P02767 source Swiss-Prot : SWS_FT_FI4 20) chain B residue 54 type BINDING sequence E description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 21) chain B residue 15 type BINDING sequence K description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1 22) chain B residue 117 type BINDING sequence S description BINDING => ECO:0000269|PubMed:11418763, ECO:0007744|PDB:1ICT source Swiss-Prot : SWS_FT_FI1

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