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eF-site ID
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5ait-B |
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PDB Code
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5ait |
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Chain
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B |
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click to enlarge
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Title
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A complex of of RNF4-RING domain, UbeV2, Ubc13-Ub (isopeptide crosslink) |
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Classification
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LIGASE/SIGNALING PROTEIN |
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Compound
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E3 UBIQUITIN-PROTEIN LIGASE RNF4 |
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Source
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(UB2V2_HUMAN) |
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Sequence
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B: |
LPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQ
DSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKL
GRIKLDILADKWSPALQIRTVLLSIQALLSAPNPDDPLAN
DVAEQWKTNEAQAIETARAWTRLYAMN
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Description
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(1) |
E3 UBIQUITIN-PROTEIN LIGASE RNF4 (E.C.6.3.2.-), UBIQUITIN-CONJUGATING ENZYME E2 N (E.C.6.3.2.19), POLYUBIQUITIN-C, UBIQUITIN-CONJUGATING ENZYME E2 VARIANT 2
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Functional site
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1)
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chain |
B |
| residue |
92 |
| type |
CROSSLNK |
| sequence |
A
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ISG15) => ECO:0000269|PubMed:16112642, ECO:0000269|PubMed:16122702
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| source |
Swiss-Prot : SWS_FT_FI3
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2)
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chain |
B |
| residue |
82 |
| type |
MOD_RES |
| sequence |
K
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| description |
N6-acetyllysine => ECO:0007744|PubMed:19608861
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| source |
Swiss-Prot : SWS_FT_FI2
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