eF-site ID 5agt-A PDB Code 5agt Chain A click to enlarge Title Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-4-chloro-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP Classification LIGASE Compound LEUCINE--TRNA LIGASE Source Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (SYL_MYCTU) Sequence A:  GAVALFSARAVDIEVFTTRPDTLFGATYLVLAPEHDLVDE LVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLER QKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAV PGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVN SDYLNGMSVPAAKRAIVDRLESAGRGRARI Description Functional site 1) chain A residue 335 type sequence F description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 2) chain A residue 336 type sequence T description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 3) chain A residue 337 type sequence T description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 4) chain A residue 338 type sequence R description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 5) chain A residue 341 type sequence T description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 6) chain A residue 430 type sequence Y description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 7) chain A residue 431 type sequence V description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 8) chain A residue 432 type sequence L description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 9) chain A residue 435 type sequence Y description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 10) chain A residue 440 type sequence I description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 11) chain A residue 441 type sequence M description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 12) chain A residue 446 type sequence H description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 13) chain A residue 447 type sequence D description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 14) chain A residue 449 type sequence R description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 15) chain A residue 450 type sequence D description BINDING SITE FOR RESIDUE A2H A 1514 source : AC1 16) chain A residue 417 type sequence P description BINDING SITE FOR RESIDUE MET A 1516 source : AC2 17) chain A residue 506 type sequence A description BINDING SITE FOR RESIDUE MET A 1516 source : AC2 18) chain A residue 346 type sequence T description BINDING SITE FOR RESIDUE GOL A 1515 source : AC3 19) chain A residue 421 type sequence E description BINDING SITE FOR RESIDUE GOL A 1515 source : AC3 20) chain A residue 422 type sequence P description BINDING SITE FOR RESIDUE GOL A 1515 source : AC3 21) chain A residue 423 type sequence V description BINDING SITE FOR RESIDUE GOL A 1515 source : AC3 22) chain A residue 460 type sequence P description BINDING SITE FOR RESIDUE GOL A 1515 source : AC3

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