eF-site ID 5agr-A PDB Code 5agr Chain A click to enlarge Title Crystal structure of the LeuRS editing domain of Mycobacterium tuberculosis in complex with the adduct (S)-3-(Aminomethyl)-7-ethoxybenzo[c][1,2]oxaborol-1(3H)-ol-AMP Classification LIGASE Compound LEUCINE--TRNA LIGASE Source (SYL_MYCTU) Sequence A:  GAVALFSARAVDIEVFTTRPDTLFGATYLVLAPEHDLVDE LVAASWPAGVNPLWTYGGGTPGEAIAAYRRAIAAKSDLER QKTGVFLGSYAINPANGEPVPIFIADYVLAGYGTGAIMAV PGHDQRDWDFARAFGLPIVEVIAGGNISESAYTGDGILVN SDYLNGMSVPAAKRAIVDRLESAGRGRARI Description Functional site 1) chain A residue 335 type sequence F description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 2) chain A residue 336 type sequence T description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 3) chain A residue 337 type sequence T description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 4) chain A residue 338 type sequence R description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 5) chain A residue 430 type sequence Y description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 6) chain A residue 431 type sequence V description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 7) chain A residue 432 type sequence L description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 8) chain A residue 435 type sequence Y description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 9) chain A residue 440 type sequence I description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 10) chain A residue 441 type sequence M description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 11) chain A residue 446 type sequence H description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 12) chain A residue 447 type sequence D description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 13) chain A residue 449 type sequence R description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 14) chain A residue 450 type sequence D description BINDING SITE FOR RESIDUE A52 A 1514 source : AC1 15) chain A residue 331 type sequence D description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 16) chain A residue 332 type sequence I description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 17) chain A residue 333 type sequence E description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 18) chain A residue 354 type sequence H description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 19) chain A residue 400 type sequence Q description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 20) chain A residue 437 type sequence T description BINDING SITE FOR RESIDUE EDO A 1515 source : AC2 21) chain A residue 319 type sequence S description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3 22) chain A residue 415 type sequence I description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3 23) chain A residue 417 type sequence P description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3 24) chain A residue 420 type sequence G description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3 25) chain A residue 502 type sequence R description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3 26) chain A residue 506 type sequence A description Binding site for Di-peptide MET A 1 and LEU A 2 source : AC3

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