eF-site ID 5ac8-A PDB Code 5ac8 Chain A click to enlarge Title S. enterica HisA with mutations D10G, dup13-15, G102A Classification ISOMERASE Compound 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Source Salmonella enterica subsp. enterica serovar Cubana str. 76814 (A0A630AQ07_SALER) Sequence A:  MIIPALDLIGGTVVRVQRDYGNDPLPRLQDYAAQGAGVLH LVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEED VAALLKAGVARVVIASTAVKSPDVVKGWFERFGAQALVLA LDVRIDEHGTKQVAVSGWQENSGVSLEQLVETYLPVGLKH VLCTDISRDGTLVSLYEEVCARYPQIAFQSSGGIGDIDDI AALRGTGVRGVIVGRALLEGKFTVKEAIQCWQN Description Functional site 1) chain A residue 81 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1245 source : AC1 2) chain A residue 82 type sequence V description BINDING SITE FOR RESIDUE SO4 A 1245 source : AC1 3) chain A residue 83 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1245 source : AC1 4) chain A residue 102 type sequence A description BINDING SITE FOR RESIDUE SO4 A 1245 source : AC1 5) chain A residue 103 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1245 source : AC1 6) chain A residue 225 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC2 7) chain A residue 226 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC2 8) chain A residue 1 type sequence M description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC3 9) chain A residue 148 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC3 10) chain A residue 220 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC3 11) chain A residue 7 type ACT_SITE sequence D description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 12) chain A residue 129 type ACT_SITE sequence D description Proton donor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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