eF-site ID 5ac7-AB PDB Code 5ac7 Chain A, B click to enlarge Title S. enterica HisA with mutations D7N, D10G, dup13-15 Classification ISOMERASE Compound 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Source Salmonella enterica subsp. enterica serovar Cubana str. 76814 (A0A630AQ07_SALER) Sequence A:  MIIPALNLIGGTVVRVVRLHQGDYARQRDYGNDPLPRLQD YAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQ VGGGVRTEEDVAALLKAGVARVVIGSTAVKSPDVVKGWFE RFGAQALVLALDVRIDEHGTKQVAVSGWQENSGVSLEQLV ETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQI AFQSSGGIGDIDDIAALRGTGVRGVIVGRALLEGKFTVKE AIQCWQ B:  MIIPALNLIGGTVVRVVRLHQGDYARQRDYGNDPLPRLQD YAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQ VGGGVRTEEDVAALLKAGVARVVIGSTAVKSPDVVKGWFE RFGAQALVLALDVRIDEHGTKQVAVSGWQENSGVSLEQLV ETYLPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQI AFQSSGGIGDIDDIAALRGTGVRGVIVGRALLEGKFTVKE AIQCWQN Description Functional site 1) chain A residue 193 type sequence R description BINDING SITE FOR RESIDUE GOL B 1245 source : AC1 2) chain B residue 193 type sequence R description BINDING SITE FOR RESIDUE GOL B 1245 source : AC1 3) chain B residue 194 type sequence Y description BINDING SITE FOR RESIDUE GOL B 1245 source : AC1 4) chain B residue 195 type sequence P description BINDING SITE FOR RESIDUE GOL B 1245 source : AC1 5) chain B residue 196 type sequence Q description BINDING SITE FOR RESIDUE GOL B 1245 source : AC1 6) chain A residue 193 type sequence R description BINDING SITE FOR RESIDUE GOL A 1244 source : AC2 7) chain A residue 194 type sequence Y description BINDING SITE FOR RESIDUE GOL A 1244 source : AC2 8) chain A residue 195 type sequence P description BINDING SITE FOR RESIDUE GOL A 1244 source : AC2 9) chain A residue 196 type sequence Q description BINDING SITE FOR RESIDUE GOL A 1244 source : AC2 10) chain B residue 193 type sequence R description BINDING SITE FOR RESIDUE GOL A 1244 source : AC2 11) chain A residue 1 type sequence M description BINDING SITE FOR RESIDUE NA A 1245 source : AC3 12) chain A residue 2 type sequence I description BINDING SITE FOR RESIDUE NA A 1245 source : AC3 13) chain A residue 243 type sequence Q description BINDING SITE FOR RESIDUE NA A 1245 source : AC3 14) chain B residue 177 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1246 source : AC4 15) chain B residue 203 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1246 source : AC4 16) chain B residue 225 type sequence G description BINDING SITE FOR RESIDUE SO4 B 1246 source : AC4 17) chain B residue 226 type sequence R description BINDING SITE FOR RESIDUE SO4 B 1246 source : AC4 18) chain A residue 176 type sequence D description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 19) chain A residue 177 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 20) chain A residue 203 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 21) chain A residue 204 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 22) chain A residue 225 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 23) chain A residue 226 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1246 source : AC5 24) chain A residue 131 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 25) chain A residue 145 type sequence W description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 26) chain A residue 174 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 27) chain B residue 15 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 28) chain B residue 25 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 29) chain B residue 230 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1247 source : AC6 30) chain A residue 7 type ACT_SITE sequence N description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 31) chain B residue 7 type ACT_SITE sequence N description Proton acceptor => ECO:0000250 source Swiss-Prot : SWS_FT_FI1 32) chain A residue 129 type ACT_SITE sequence D description Proton donor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2 33) chain B residue 129 type ACT_SITE sequence D description Proton donor => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

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