eF-site ID 5a91-A PDB Code 5a91 Chain A click to enlarge Title 15K X-ray ligand free: Exploring the Mechanism of beta-Lactam Ring Protonation in the Class A beta-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography Classification HYDROLASE Compound SULFATE ION Source (BLC97_ECOLX) Sequence A:  SVQQQLEALEKSSGGRLGVALINTADNSQILYRADERFAM CSTSKVMAAAAVLKQSESDKHLLNQRVEIKKSDLVNYNPI AEKHVNGTMTLAELGAAALQYSDNTAMNKLIAHLGGPDKV TAFARSLGDETFRLDRTAPTLNTAIPGDPRDTTTPLAMAQ TLKNLTLGKALAETQRAQLVTWLKGNTTGSASIRAGLPKS WVVGDKTGSGDYGTTNDIAVIWPENHAPLVLVTYFTQPEQ KAENRNDILAAAAKIVTHGF Description (1)  PROTEIN Functional site 1) chain A residue 70 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 2) chain A residue 130 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 3) chain A residue 234 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 4) chain A residue 235 type sequence T description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 5) chain A residue 236 type sequence G description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 6) chain A residue 237 type sequence S description BINDING SITE FOR RESIDUE SO4 A 1291 source : AC1 7) chain A residue 229 type sequence W description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 8) chain A residue 252 type sequence P description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 9) chain A residue 254 type sequence E description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 10) chain A residue 255 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 11) chain A residue 256 type sequence H description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 12) chain A residue 290 type sequence F description BINDING SITE FOR RESIDUE SO4 A 1292 source : AC2 13) chain A residue 82 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1293 source : AC3 14) chain A residue 198 type sequence A description BINDING SITE FOR RESIDUE SO4 A 1293 source : AC3 15) chain A residue 274 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1293 source : AC3 16) chain A residue 276 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1293 source : AC3 17) chain A residue 277 type sequence D description BINDING SITE FOR RESIDUE SO4 A 1293 source : AC3 18) chain A residue 88 type sequence K description BINDING SITE FOR RESIDUE SO4 A 1294 source : AC4 19) chain A residue 89 type sequence H description BINDING SITE FOR RESIDUE SO4 A 1294 source : AC4 20) chain A residue 92 type sequence N description BINDING SITE FOR RESIDUE SO4 A 1294 source : AC4 21) chain A residue 52 type sequence A description BINDING SITE FOR RESIDUE SO4 A 1295 source : AC5 22) chain A residue 178 type sequence R description BINDING SITE FOR RESIDUE SO4 A 1295 source : AC5 23) chain A residue 70 type ACT_SITE sequence S description Acyl-ester intermediate => ECO:0000255|PROSITE-ProRule:PRU10101 source Swiss-Prot : SWS_FT_FI1 24) chain A residue 66-81 type prosite sequence FAMCSTSKVMAAAAVL description BETA_LACTAMASE_A Beta-lactamase class-A active site. FaMCSTsKvmaAAAVL source prosite : PS00146 25) chain A residue 234 type BINDING sequence K description BINDING => ECO:0000250 source Swiss-Prot : SWS_FT_FI2

Display surface Download Links