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eF-site ID
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5a5b-9 |
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PDB Code
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5a5b |
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Chain
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9 |
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click to enlarge
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Title
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Structure of the 26S proteasome-Ubp6 complex |
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Classification
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HYDROLASE |
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Compound
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PROTEASOME COMPONENT PRE3 |
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Source
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ORGANISM_COMMON: BAKER'S YEAST; ORGANISM_SCIENTIFIC: SACCHAROMYCES CEREVISIAE; |
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Sequence
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9: |
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQ
QRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGX
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Description
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(1) |
PROTEASOME COMPONENT PRE3 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP1 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP3 (E.C.3.4.25.1), PROTEASOME COMPONENT C11 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE2 (E.C.3.4.25.1), PROTEASOME COMPONENT C5 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE4 (E.C.3.4.25.1), UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 6 (E.C.3.1.2.15), UBIQUITIN ALDEHYDE, PROTEASOME COMPONENT C7-ALPHA (E.C.3.4.25.1), PROTEASOME COMPONENT Y7 (E.C.3.4.25.1), PROTEASOME COMPONENT Y13 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE6 (E.C.3.4.25.1), PROTEASOME COMPONENT PUP2 (E.C.3.4.25.1), PROTEASOME COMPONENT PRE5 (E.C.3.4.25.1), 26S PROTEASE REGULATORY SUBUNIT 7 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, 26S PROTEASE SUBUNIT RPT4, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASOME REGULATORY SUBUNIT RPN2, 26S PROTEASOME REGULATORY SUBUNIT RPN9, 26S PROTEASOME REGULATORY SUBUNIT RPN5, 26S PROTEASOME REGULATORY SUBUNIT RPN6, 26S PROTEASOME REGULATORY SUBUNIT RPN7, 26S PROTEASOME REGULATORY SUBUNIT RPN3, 26S PROTEASOME REGULATORY SUBUNIT RPN12, 26S PROTEASOME REGULATORY SUBUNIT RPN8, 26S PROTEASOME REGULATORY SUBUNIT RPN11, 26S PROTEASOME REGULATORY SUBUNIT RPN10, 26S PROTEASOME REGULATORY SUBUNIT RPN13, 26S PROTEASOME COMPLEX SUBUNIT SEM1
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Functional site
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1)
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chain |
9 |
| residue |
76 |
| type |
MOD_RES |
| sequence |
X
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| description |
ADP-ribosylglycine => ECO:0000269|PubMed:28525742
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| source |
Swiss-Prot : SWS_FT_FI5
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2)
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chain |
9 |
| residue |
63 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
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| source |
Swiss-Prot : SWS_FT_FI12
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|
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3)
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chain |
9 |
| residue |
6 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603
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| source |
Swiss-Prot : SWS_FT_FI6
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4)
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chain |
9 |
| residue |
27-52 |
| type |
prosite |
| sequence |
KAKIQDKEGIPPDQQRLIFAGKQLED
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| description |
UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD
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| source |
prosite : PS00299
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5)
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chain |
9 |
| residue |
29 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
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| source |
Swiss-Prot : SWS_FT_FI10
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6)
|
chain |
9 |
| residue |
33 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
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| source |
Swiss-Prot : SWS_FT_FI11
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|
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7)
|
chain |
9 |
| residue |
27 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
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| source |
Swiss-Prot : SWS_FT_FI9
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8)
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chain |
9 |
| residue |
76 |
| type |
CROSSLNK |
| sequence |
X
|
| description |
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
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| source |
Swiss-Prot : SWS_FT_FI7
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|
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9)
|
chain |
9 |
| residue |
11 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
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| source |
Swiss-Prot : SWS_FT_FI8
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10)
|
chain |
9 |
| residue |
48 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
|
| source |
Swiss-Prot : SWS_FT_FI8
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