eF-site ID 5a0w-ADG PDB Code 5a0w Chain A, D, G click to enlarge Title THE CRYSTAL STRUCTURE OF I-DMOI E117A IN COMPLEX WITH ITS TARGET DNA AND IN THE PRESENCE OF 2MM MN Classification HYDROLASE/DNA Compound HOMING ENDONUCLEASE I-DMOI Source Desulfurococcus mobilis (5A0W) Sequence A:  ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS KKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKR LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN ISLRDRIKFVHTILSSHLNPLP D:  ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS KKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKR LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN ISLRDRIKFVHTILSSHLNPLPPEAAALEHH G:  ENVSGISAYLLGLIIGDGGLYKLKYKGNRSEYRVVITQKS ENLIKQHIAPLMQFLIDELNVKSKIQIVKGDTRYELRVSS KKLYYYFANMLERIRLFNMREQIAFIKGLYVAAGDKTLKR LRIWNKNKALLEIVSRWLNNLGVRNTIHLDDHRHGVYVLN ISLRDRIKFVHTILSSHL Description Functional site 1) chain A residue 66 type sequence K description BINDING SITE FOR RESIDUE CL A 1187 source : AC1 2) chain A residue 111 type sequence K description BINDING SITE FOR RESIDUE ACT A 1188 source : AC2 3) chain A residue 182 type sequence L description BINDING SITE FOR RESIDUE ACT A 1188 source : AC2 4) chain A residue 183 type sequence N description BINDING SITE FOR RESIDUE ACT A 1188 source : AC2 5) chain A residue 117 type sequence A description BINDING SITE FOR RESIDUE ACT C 1026 source : AC4 6) chain D residue 114 type sequence Y description BINDING SITE FOR RESIDUE CL D 1196 source : AC6 7) chain G residue 20 type sequence G description BINDING SITE FOR RESIDUE ACT I 1026 source : BC1 8) chain G residue 117 type sequence A description BINDING SITE FOR RESIDUE ACT I 1026 source : BC1 9) chain A residue 21 type sequence D description BINDING SITE FOR RESIDUE MN A 1189 source : BC3 10) chain A residue 116 type sequence A description BINDING SITE FOR RESIDUE MN A 1189 source : BC3 11) chain D residue 21 type sequence D description BINDING SITE FOR RESIDUE MN D 1197 source : BC4 12) chain D residue 116 type sequence A description BINDING SITE FOR RESIDUE MN D 1197 source : BC4 13) chain G residue 21 type sequence D description BINDING SITE FOR RESIDUE MN G 1183 source : BC6 14) chain G residue 116 type sequence A description BINDING SITE FOR RESIDUE MN G 1183 source : BC6 15) chain A residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 16) chain A residue 117 type ACT_SITE sequence A description source Swiss-Prot : SWS_FT_FI1 17) chain D residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 18) chain D residue 117 type ACT_SITE sequence A description source Swiss-Prot : SWS_FT_FI1 19) chain G residue 21 type ACT_SITE sequence D description source Swiss-Prot : SWS_FT_FI1 20) chain G residue 117 type ACT_SITE sequence A description source Swiss-Prot : SWS_FT_FI1

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