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eF-site ID
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4zux-X |
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PDB Code
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4zux |
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Chain
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X |
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click to enlarge
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Title
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SAGA DUB module Ubp8/Sgf11/Sus1/Sgf73 bound to ubiqitinated nucleosome |
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Classification
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Hydrolase/DNA |
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Compound
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Histone H3.2 |
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Source
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Xenopus laevis (African clawed frog) (SGF73_YEAST) |
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Sequence
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X: |
MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQ
QRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGG
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Description
|
(1) |
Histone H3.2, Histone H4, Histone H2A type 1, Histone H2B 1.1, Ubiquitin carboxyl-terminal hydrolase 8, Transcription and mRNA export factor SUS1, SAGA-associated factor 11, Polyubiquitin-B, SAGA-associated factor 73/DNA Complex
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Functional site
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1)
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chain |
X |
| residue |
54 |
| type |
SITE |
| sequence |
R
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| description |
Interacts with activating enzyme
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| source |
Swiss-Prot : SWS_FT_FI1
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2)
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chain |
X |
| residue |
72 |
| type |
SITE |
| sequence |
R
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| description |
Interacts with activating enzyme
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| source |
Swiss-Prot : SWS_FT_FI1
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3)
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chain |
X |
| residue |
68 |
| type |
SITE |
| sequence |
H
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| description |
Essential for function
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| source |
Swiss-Prot : SWS_FT_FI2
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4)
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chain |
X |
| residue |
65 |
| type |
MOD_RES |
| sequence |
S
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| description |
Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291
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| source |
Swiss-Prot : SWS_FT_FI3
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5)
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chain |
X |
| residue |
66 |
| type |
MOD_RES |
| sequence |
T
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| description |
(Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457
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| source |
Swiss-Prot : SWS_FT_FI4
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6)
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chain |
X |
| residue |
76 |
| type |
MOD_RES |
| sequence |
G
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| description |
ADP-ribosylglycine => ECO:0000269|PubMed:28525742
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| source |
Swiss-Prot : SWS_FT_FI5
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7)
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chain |
X |
| residue |
6 |
| type |
CROSSLNK |
| sequence |
K
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| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603
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| source |
Swiss-Prot : SWS_FT_FI6
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8)
|
chain |
X |
| residue |
76 |
| type |
CROSSLNK |
| sequence |
G
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| description |
Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)
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| source |
Swiss-Prot : SWS_FT_FI7
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9)
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chain |
X |
| residue |
11 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
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| source |
Swiss-Prot : SWS_FT_FI8
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10)
|
chain |
X |
| residue |
48 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144
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| source |
Swiss-Prot : SWS_FT_FI8
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|
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11)
|
chain |
X |
| residue |
29 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127
|
| source |
Swiss-Prot : SWS_FT_FI10
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|
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12)
|
chain |
X |
| residue |
33 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577
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| source |
Swiss-Prot : SWS_FT_FI11
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13)
|
chain |
X |
| residue |
63 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106
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| source |
Swiss-Prot : SWS_FT_FI12
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14)
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chain |
X |
| residue |
27 |
| type |
CROSSLNK |
| sequence |
K
|
| description |
Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860
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| source |
Swiss-Prot : SWS_FT_FI9
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